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PeroxisomeDB


NAR Molecular Biology Database Collection entry number 1001
SchlÜter A.1, Fourcade S.1, DomÈnech-EstÉvez E.1, GabaldÓn T.2, Huerta-Cepas J.2, Berthommier G.3, Ripp R.3, Wanders R.J.A. 4, Poch O.3 and Pujol A.1,5
1Centre de GenÈtica MÈdica i Molecular, Institut d'InvestigaciÓ BiomÈdica de Bellvitge-Institut de Recerca OncolÒgica (IDIBELL-IRO), Hospital Duran i Reynals Gran via Km 2,7. 08907 L'Hospitalet del Llobregat, Spain
2Bioinformatics Department Centro de InvestigaciÓn PrÍncipe Felipe, Avda. Autopista del Saler, 16 Valencia 46013, Spain
3Institut de GÉnÉtique et de Biologie MolÉculaire et Cellulaire, CNRS/INSERM/ULP/CollÈge de France, 1 rue Laurent Fries, BP10142 67404 Illkirch Cedex, France
4AMC, Laboratory of Genetic Metabolic Diseases, Amsterdam, The Netherlands
5InstituciÓ Catalana de Recerca i Estudis Avan├žats (ICREA)
Contact apujol@iro.es

Database Description

PeroxisomeDB (http://www.peroxisomeDB.org) is a peroxisomal database that includes the complete peroxisomal proteome of Homo sapiens and Saccharomyces cerevisiae, structured in interrelated sections 'Genes', 'Functions' 'Metabolic pathways' and 'Diseases', with hyperlinks to selected features of NCBI, ENSEMBL and UCSC databases. We have designed graphical depictions of the main peroxisomal metabolic routes and have included updated flow charts for diagnosis. Precomputed BLAST, PSI-BLAST, multiple sequence alignment (MUSCLE) and phylogenetic trees are provided to study evolutionary conserved functions and pathways. Highlights of the PeroxisomeDB include new tools developed for facilitating i) identification of novel peroxisomal proteins and ii) detection of peroxisomes in silico.

Acknowledgements

This database is supported by funds from the Institut National de la SantÉ et de la Recherche MÉdicale, the Centre National de la Recherche Scientifique, the European Commission contract LSHM-CT2004-502987, the Association Fran├žaise contre les Myopathies (Decrypthon Program) the European Leukodystrophy Association, the AsociaciÓn EspaÑola contra la Leucodistrofia (ALE-ELA EspaÑa) and Fondo de InvestigaciÓn Sanitario (FIS) from the Instituto de Salud Carlos III


Go to the abstract in the NAR 2010 Database Issue.
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