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KDBI


NAR Molecular Biology Database Collection entry number 138
Ji Z.L.1, Han B.C.1, Wang Y.P.1, Zhang Y.T.1, Liang L.1, Han L.Y.2, Zheng C.J.2, Chen Y.Z.2
1Bioinformatics Research Group, School of Life Sciences, Xiamen University, Xiamen 361005, FuJian Province, P R China
2Department of Computational Science, National University of Singapore, Blk S17, Level 7, 3 Science Drive 2, Singapore 117543

Database Description

KDBI is a collection of experimentally determined kinetic data of protein-protein, protein-nucleic acids, protein-ligand, nucleic acids-ligand binding or reaction events described in the literature.

Since its first opening for public access in 2003, many efforts have been made continuously to improve this database both in database size and data representation methods. Currently, KDBI contains 20,803 entries (about 2.5 fold of 8,273 in year 2003) of 11,916 distinctive bio-molecular binding or interaction events, which involve 2,934 proteins, 870 nucleic acids and 6,713 small molecules. A new user-friendly search engine is developed for more accurate and efficient query, and a graphic interface is also designed for better representation of data. Moreover, more than 20 kinetic protein-protein interaction maps are constructed for better data visualization and further quantitative study of biological pathway.

The KDBI can be accessed either at http://bidd.nus.edu.sg/group/kdbi/kdbi.asp (Hosted by Bioinformatics & Drug Design group, National University of Singapore, Singapore) or at http://bioinf.xmu.edu.cn/databases/kdbi/kdbi.php (Hosted by Bioinformatics Research Group of Xiamen University, P R China).

References

1. Ji ZL, Chen X, Zhen CJ, Yao LX, Han LY, Yeo WK, Chung PC, Puy HS, Tay YT, Muhammad A, Chen YZ. (2003) KDBI: Kinetic Data of Bio-molecular Interactions database. Nucleic Acids Res. 31:255-257.

Subcategory: Protein properties

Go to the abstract in the NAR 2009 Database Issue.
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