HMDD v2.0 - Human microRNA Disease Database version 2.0

NAR Molecular Biology Database Collection entry number 1680
ng Li1,2, Chengxiang Qiu3, Jian Tu2,4, Bin Geng4, Jichun Yang4, Tianzi Jiang3 and Qinghua Cui2,4
1 Department of Cell Biology, School of Basic Medical Sciences, Peking University, 38 Xueyuan Rd, Beijing, 100191, China 2 Department of Biomedical Informatics, School of Basic Medical Sciences, Peking University, 38 Xueyuan Rd, Beijing, 100191, China 3 Institute of Automation, Chinese Academy of Sciences, Beijing, 100190, China. 4 MOE Key Lab of Cardiovascular Sciences, Peking University, 38 Xueyuan Road, Beijing, 100191, China

Database Description

The HMDD database is a collection of experimentally supported human microRNA (miRNA) and disease associations. Here, we describe the HMDD v2.0 update that presented several novel options for users to facilitate exploration of the data in the database. By keeping datasets up-to-date, HMDD should continue to serve as a valuable resource for investigating the roles of miRNAs in human disease.

Recent Developments

In the updated database, miRNA-disease association data were annotated in more details. For example, miRNA-disease association data from genetics, epigenetics, circulating miRNAs, and miRNA-target interactions were integrated into the database. In addition, HMDD v2.0 presented more data that were generated based on concepts derived from the miRNA-disease association data, including disease spectrum width of miRNAs and miRNA spectrum width of human diseases. Moreover, we provided users a link to download all the data in the HMDD v2.0 and a link to submit novel data into the database. Meanwhile, we also maintained the old version of HMDD.

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