MitoBreak - The mitochondrial DNA breakpoints database
NAR Molecular Biology Database Collection entry number 1740
Damas, J.1, Carneiro, J. 1, Amorim, A. 1, 2, Pereira, F. 1,3
1Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Rua Dr. Roberto Frias s/n, Porto, Portugal. 2Faculty of Sciences, University of Porto, Rua do Campo Alegre, Porto, Portugal 3Interdisciplinary Centre of Marine and Environmental Research (CIIMAR/CIMAR), University of Porto, Rua dos Bragas 289, Porto, Portugal
The mitochondrial DNA breakpoints database (MitoBreak) describes breakpoints from circular deleted (deletions), circular partially-duplicated (duplications) and linear mitochondrial DNA molecules. The database was originally built with more than 1400 mtDNA rearrangements from different species and their associated phenotypic information collected from nearly 400 publications. The MitoBreak allows researchers to (1) perform multiple types of data analyses through user-friendly interfaces with full or partial datasets, (2) access the precise breakpoint positions, junction sequences, disease or associated symptoms, and links to the related publications, (3) download all the available data, (4) correct the location of new breakpoints and (5) submit new mtDNA rearrangements.
Portuguese Foundation for Science and Technology (FCT)
Category: Organelle databases
Subcategory: Mitochondrial genes and proteins
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