lncRNASNP


NAR Molecular Biology Database Collection entry number 1767
Guo, An-Yuan; Gong, Jing; Liu, Wei.; Zhang, Jiayou; Miao, Xiaoping
Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei, 430074, PR China

Database Description

lncRNASNP is an integrated database of SNPs in lncRNAs and their potential functions in human and mouse. It integrated several public databases and tools, including LNCipedia, NONCODE, dbSNP, miRBase, TCGA and so on. Its aim is to provide information of SNPs in lncRNAs, structure change by SNP, the binding sites of lncRNA:miRNA and potential functional SNPs which can impact lncRNA:miRNA interaction. In addition, lncRNASNP also integrates GWAS data and miRNA expression data into functional SNP selection for genetic association studies. Currently, users can:
Browse or search SNPs in lncRNAs and their impacts on RNA secondary structure;
Browse or search miRNA binding sites in lncRNAs;
Browse or search SNPs impacting the interaction of miRNA:lncRNA (loss or gain);
Browse or search SNPs in GWAS linkage disequilibrium (LD) regions;
Browse or search miRNA expression data to prioritize functional SNP selection.

Acknowledgements

This project was supported by grants from NSFC.

References

Gong Jing, Liu Wei, Miao Xiaoping, Guo An-Yuan. lncRNASNP: a database of SNPs in lncRNAs and their potential functions in human and mouse. Nucleic Acids Research. 2015(Database issue). pii: gku1000.


Go to the abstract in the NAR 2015 Database Issue.
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