LncRNAWiki


NAR Molecular Biology Database Collection entry number 1768
Ma, Lina; Li, Ang; Zou, Dong; Yu, Jun; Bajic, Vladimir; Zhang, Zhang
1 CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China 2 University of Chinese Academy of Sciences, Beijing 100049, China 3 King Abdullah University of Science and Technology (KAUST), Computational Bioscience Research Center (CBRC), Computer, Electrical and Mathematical Sciences and Engineering Division (CEMSE), Thuwal 23955-6900, Kingdom of Saudi Arabia

Database Description

LncRNAWiki (http://lncrna.big.ac.cn) is a wiki-based, open-content, and publicly editable platform aimed at community-based curation and collection of information on human long non-coding RNAs (lncRNAs). Current related databases are dependent primarily on curation by experts, making it laborious to annotate the exponentially accumulated information on lncRNAs, which inevitably requires collective efforts in community-based curation of lncRNAs. Unlike existing databases, lncRNAWiki features comprehensive integration of information on human lncRNAs obtained from multiple different resources and allows not only existing lncRNAs to be edited, updated and curated by different users but also the addition of newly identified lncRNAs by any user. It harnesses community collective knowledge in collecting, editing, and annotating human lncRNAs and rewards community-curated efforts by providing explicit authorship based on quantified contributions. LncRNAWiki relies on the underling knowledge of scientific community for collective and collaborative curation of human lncRNAs and thus has the potential to serve as an up-to-date and comprehensive knowledgebase for human lncRNAs.

Acknowledgements

We thank members of the Zhang Lab for reporting bugs and sending comments. LncRNAWiki is funded by the Strategic Priority Research Program of the Chinese Academy of Sciences, the National Natural Science Foundation of China, the Base Research Fund of King Abdullah University of Science and Technology, and the ‘100-Talent Program’ of Chinese Academy of Sciences.

References

1. Salzberg SL. Genome re-annotation: a wiki solution? Genome Biol. 2007;8:102.
2. Howe D, Costanzo M, Fey P, Gojobori T, Hannick L, Hide W, Hill DP, Kania R, Schaeffer M, St Pierre S, et al . Big data: The future of biocuration. Nature 2008;455:47-50.
3. Finn RD, Gardner PP, Bateman A. Making your database available through Wikipedia: the pros and cons. Nucleic Acids Res. 2012;40:D9-D12.
4. Dai L, Tian M, Wu J, Xiao J, Wang X, Townsend JP, Zhang Z. AuthorReward: increasing community curation in biological knowledge wikis through automated authorship quantification. Bioinformatics 2013;29:1837-1839.
5. Ma L, Bajic V, Zhang Z. On the classification of long non-coding RNAs.RNA Biology 2013;10: 925-33.


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