NUREBASE
NAR Molecular Biology Database Collection entry number 183
Ruau, D.1, Duarte, J.1, Ourjdal, T.1, Perrière, G.2, Laudet, V.1, Robinson-Rechavi, M.1
1Laboratoire de Biologie Moléculaire et Cellulaire, UMR CNRS 5665, Ecole Normale Supérieure de Lyon 46, allée d'Italie 69364 LYON cédex 07, France
2Laboratoire de Biométrie et Biologie Évolutive, UMR CNRS 5558, Université Claude Bernard - Lyon 1 43, bd. du 11 Novembre 1918, 69622 Villeurbanne Cedex, France
2Laboratoire de Biométrie et Biologie Évolutive, UMR CNRS 5558, Université Claude Bernard - Lyon 1 43, bd. du 11 Novembre 1918, 69622 Villeurbanne Cedex, France
Contact nurebase@listes.ens-lyon.fr
Database Description
Nuclear hormone receptors are an abundant class of ligand activated transcriptional regulators, found in varying numbers in all animals. Based on our experience of managing the official nomenclature of nuclear receptors, we have developed NUREBASE, a database containing protein and DNA sequences, reviewed protein alignments and phylogenies, taxonomy and annotations for all nuclear receptors. The reviewed NUREBASE is completed by NUREBASE_DAILY, automatically updated every 24 hours. Both databases are accessible through a World-Wide Web server, which allows simple as well as complex queries, and manipulation of alignments and phylogenies, as well as simimlarity searches against NUREBASE. All information on accessing and installing NUREBASE may be found at http://www.ens-lyon.fr/LBMC/laudet/nurebase/nurebase.html.
Recent Developments
NUREBASE version 2 includes standardized names for coding sequences, with annotation of alternative transcripts. Expression patterns deduced from EST data are represented by standardized keywords for human; extension to other species is under progress.
Acknowledgements
NUREBASE is supported by the CNRS.
Category: Protein sequence databases
Subcategory: Protein localization and targeting
Category: Protein sequence databases
Subcategory: Databases of individual protein families
Go to the abstract in the NAR 2004 Database Issue.
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