16S and 23S Ribosomal RNA Mutation Database

NAR Molecular Biology Database Collection entry number 229
Triman K.L.
Department of Biology, Franklin and Marshall College, Lancaster, PA 17604, USA

Database Description

Access to the expanded versions of the 16S and 23S Ribosomal RNA Mutation Databases has been improved to permit searches of the lists of alterations for all the data from (1) one specific organism, (2) one specific nucleotide position, (3) one specific phenotype, or (4) a particular author. The URL for the searchable version of the Databases is: http://ribosome.fandm.edu. The database currently consists of 1024 records, including 485 16S rRNA records from Escherichia coli, 37 16S-like rRNA records from other organisms, 421 23S rRNA records from E. coli, and 81 23S-like records from other organisms. The numbering of positions in all records corresponds to the numbering in E. coli. We welcome any suggested revisions to the database, as well as information about newly characterized 16S or 23S rRNA mutations.

Recent Developments

We plan to expand the database to include mutations in ribosomal proteins and ribosomal factors. The expanded database will be called The Ribosomal Mutation Database. Please send bibliographic citations for published work to be included in The Ribosomal Mutation Database to the curator by email at ktriman@fandm.edu.


We are grateful to Janan Eppig, Carol Bult, and Debra Krupke from the Bioinformatics Group at the Jackson Laboratory for their expert advice on the use of appropriate database software. This work was supported by the National Science Foundation (MCB-9726951).

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