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ASC - Active Sequence Collection


NAR Molecular Biology Database Collection entry number 374
Angelo Facchiano1, Antonio Facchiano2, Francesco Facchiano2
1Istituto di Scienze dell'Alimentazione - CNR via Roma 52A/C, 83100 Avellino ITALY
2IDI - Istituto Dermopatico dell'Immacolata - via Monti di Creta 104, 00167 Roma ITALY

Database Description

ASC (Active Sequences Collection) is a database of short amino acid sequences with known biological activity. The current version is substantially improved as compared to the previous release; it now includes more than 1300 different active short protein sequences, each sequence being linked to the corresponding PUBMED literature reference. The entries are organized in six sections (3 more than the previous release): AIRS (Autoimmunity Related Sequences), DVP (Delivery Vectors Peptides), SSP (Structure of Solved Peptides), BAC (BioACtive peptides), DORRS (Database Of RGD Related Sequences), and TRANSIT (TRANsglutamination SITes). This release is characterized by a relevant reorganization of the structural and functional information, and increase of literature references and links to other databases. Aim of ASC is to help elucidating the biological role of proteins and to help new-drugs discovery. The main feature of this collection is the focus on specific biological functions and the lack of "noisy" signal. The web address to access ASC database is: http://bioinformatica.isa.cnr.it/ASC/ which also offers a new query interface to compare protein sequences with the ASC collection, as well as an updating interface to allow contribution of new referenced active sequences from the users.

References

Facchiano, A., Facchiano, A., and Facchiano, F. ASC (Active Sequences Collection) database: a new tool to assign functions to protein sequences. Nucleic Acids Research 2003 Database Issue, accepted.


Go to the abstract in the NAR 2003 Database Issue.
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