anti-CRISPRdb


NAR Molecular Biology Database Collection entry number 60
Guo, Feng-Biao; Dong, Chuan; Hao, Ge-Fei; Hua, Hong-Li; Liu, Shuo; Labena, Abraham; Chai, Guoshi; Huang, Jian.,; Rao, Nini
1 School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, P. R. China;
2 Center for Informational Biology, University of Electronic Science and Technology of China, Chengdu 610054, P. R. China;
3 Key Laboratory for Neuro-information of the Ministry of Education, University of Electronic Science and Technology of China, Chengdu 610054, P. R. China;
4 Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China

Database Description

Anti-CRISPRdb is a comprehensive online resource that effectively organizes anti-CRISPR proteins determined by experimental and bioinformatics methods. Additionally, it also provides nucleotide sequences, interactors, three-dimensional structures, and similarities against virulence factors for each anti-CRISPR. In terms of those potential anti-CRISPRs, we provide the similarity of potential and verified anti-CRISPRs, consequently, users can explore these proteins from different aspects.
Users can not only browse, search, blast, screen, and download data on their interested anti- CRISPRs, but can also share data on validated/potential anti-CRISPR proteins with other related scientific communities. Hence, our database is a user-friendly database that encourages data sharing.

Acknowledgements

We would like to thank Dr. Alan R. Davidson who kindly provided us with four anti-CRISPRs that have anti-I- E activity, and Dr. Jian Yang, who kindly replied our questions about the VFDB database. Additionally,

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Go to the abstract in the NAR 2018 Database Issue.
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