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CandidaDB


NAR Molecular Biology Database Collection entry number 617
C. d’Enfert1, S. Goyard1, S. Rodriguez-Arnaveilhe1, L. Frangeul2, L. Jones3, F. Tekaia4, O. Bader5, A. Albrecht5, L. Castillo6, A. Dominguez7, J. Ernst8, C. Fradin5, C. Gaillardin9, S. Garcia-Sanchez1, P. de Groot10, B. Hube5, F.M. Klis10, S. Krishnamurthy8, D. Kunze5, M.-C. Lopez7, A. Mavor11, N. Martin7, I. Moszer2, D. OnÉsime9, J. Perez Martin12, R. Sentandreu6, E. Valentin6 and A.J.P. Brown11
1UnitÉ Postulante Biologie et PathogÉnicitÉ Fongiques, INRA USC 2019,
2GÉnopole Plate-forme IntÉgration et Analyse GÉnomiques,
3Groupe Logiciels et banques de DonnÉes, and
4UnitÉ de GÉnÉtique MolÉculaire des Levures, CNRS URA 2171, DÉpartement Structure et Dynamique des GÉnomes, Institut Pasteur, Paris, France,
5Robert Koch Institute, NG4, Berlin, Germany,
6University of Valencia, Burjassot, Spain,
7Universidad de Salamanca, Salamanca, Spain,
8Heinrich-Heine-UniversitÄt, DÜsseldorf, Germany,
9Laboratoire de GÉnÉtique MolÉculaire et Cellulaire, INA-PG-INRA-CNRS, Thiverval-Grignon, France,
10Universiteit van Amsterdam, Swammerdam Institute for Life Sciences, Amsterdam, The Netherlands,
11Aberdeen University, Aberdeen, United Kingdom, and
12Centro Nacional de Biotecnologia-CSIC, Madrid, Spain

Database Description

CandidaDB is a database dedicated to the genome of the most prevalent systemic fungal pathogen of humans, Candida albicans. CandidaDB Release 2.0 (June 2004) contains information pertaining to Assembly 19 of the genome of C. albicans strain SC5314. The current release contains 6244 annotated entries corresponding to 130 tRNA genes and 5917 protein-coding genes. For these, it provides tentative functional assignments along with numerous pre-run analyses that can assist the researcher in the evaluation of gene function for the purpose of specific or large-scale analysis. CandidaDB is based on GenoList, a generic relational data schema and a World Wide Web interface that has been adapted to the handling of eukaryotic genomes. The interface allows users to easily browse through genome data and retrieve information. CandidaDB also provides more elaborate tools, such as pattern searching, that are tightly connected to the overall browsing system. Because the C. albicans genome is diploid and still incompletely assembled, CandidaDB provides tools to browse the genome by individual supercontigs and to examine information about allelic sequences obtained from complementary contigs.

Acknowledgements

Sequence data from C. albicans were obtained from the Stanford Genome Technology Center. Sequencing of C. albicans was accomplished with the support of the NIDR and the Burroughs Wellcome Fund. This work was supported by grants from the European Commission (QLK2-2000-00795; MCRTN-CT-2003-504148 ; 'Galar Fungail Consortium’) to AJPB, CE, AD, JE, CG, BH, FMK, JPM and RS and the MinistÈre de la Recherche et de la Technologie (P.R.F.M.M.I.P. 'RÉseau Infections Fongiques’) to CE and CG.


Go to the abstract in the NAR 2008 Database Issue.
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