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IPD-ESTDAB


NAR Molecular Biology Database Collection entry number 692
Robinson J., Waller M.J., Marsh S.G.E.
Anthony Nolan Research Institute, London, UK
Contact ipd@ebi.ac.uk

Database Description

The Immuno Polymorphism Database (IPD) is a set of specialist databases related to the study of polymorphic genes in the immune system. IPD currently consists of four databases: IPD-KIR, contains the allelic sequences of Killer-cell Immunoglobulin-like Receptors, IPD-MHC, is a database of sequences of the major histocompatibility complex of different species; IPD-HPA, alloantigens expressed only on platelets; and IPD-ESTAB, which provides access to the European Searchable Tumour Cell-Line Database, a cell bank of immunologically characterised melanoma cell lines.

IPD-ESTDAB is a database of immunologically characterised melanoma cell lines. The database works in conjunction with the European Searchable Tumour Cell Line Database (ESTDAB) cell bank, which is housed in TÜbingen, Germany and provides immunologically characterised tumour cells. The IPD-ESTDAB section of the website provides an online search facility for cells stored in this cell bank. This enables investigators to identify cells possessing specific parameters important for studies of immunity, immunogenetics, gene expression, metastasis, response to chemotherapy, and other tumour biological experimentation. The search tool allows for searches based on a single parameter, or clusters of parameters on over 250 different markers for each cell. The detailed reports produced can be then be used to identify cells of interest, which can then be obtained from the cell bank.

Acknowledgements


P Stoehr, European Bioinformatics Institute, UK
Ch Roberts, Anthony Nolan Research Institute, UK
IA Dodi, Anthony Nolan Research Institute, UK
F Garrido, Hospital Universitario Virgen de las Nieves, Spain
R Kiessling, Cancer Centre Karolinska, Sweden
P Laidler, Jagiellonian Universoti Medical College, Poland
E Naumova, University Hospital "Alexandrovska", Bulgaria
PT Straten, Institute of Cancer Biology, Denmark
G Pawlec, Zentrum fur Medizinische Forschung, Germany

References

1. Robinson J, Waller MJ, Parham P, de Groot N, Bontrop R, Kennedy LJ, Stoehr P, Marsh SGE. Nucleic Acids Research (2003), 31:311-314
2. Robinson J, Waller MJ, Marsh SGE. Nucleic Acids Research (2005) - Accepted for 2005 Issue.


Go to the abstract in the NAR 2005 Database Issue.
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