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IPI - International Protein Index


NAR Molecular Biology Database Collection entry number 696
Kersey, P.J., Duarte, J., Apweiler, R.
EMBL Outstation European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK

Database Description

The International Protein Index (IPI) provides a top level guide to the main databases that describe the human, mouse and rat proteomes. IPI is built from the protein sequence data taken from the UniProt Knowledgebase, Ensembl and RefSeq databases, which are combined to create proteome sets for each species that combine a level degree of completeness with a low level of redundancy. Stable identifiers (with incremental versioning) allow the tracking of sequences in IPI between IPI releases, while cross-references are provided between equivalent entries in the source databases.

Recent Developments

Secondary identifiers have been introduced to allow IPI IDs to be tracked between releases, even after two previously separate entries have been merged. Additionally, the past year has seen the introduction of cross-references from IPI to eight additional databases. In the course of the next year, we plan to extend IPI to additional metazoan proteomes and to integrate proteins sequence data from additional sources into the human IPI.

Acknowledgements

The Integr8 project is in part funded by the TEMBLOR grant (QLRI-CT-2001-00015) of the European Commission under the RTD programme 'Quality of Life and Management of Living Resources’.

References

Kersey, P.J., Duarte, J., Williams, A., Karavidopoulou, Y., Birney, E., Apweiler, R. (2004) The International Protein Index: An integrated database for proteomics experiments. Proteomics 4(7), 1985-1988.

Subcategory: Human ORFs

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