NAR Molecular Biology Database Collection entry number 724

http://pbil.univ-lyon1.fr/polymorphix/query.php

Bazin E.¹, Duret L.², Penel S.², and Galtier N.¹

¹Laboratoire "Génome Populations Interactions Adaptation", Unité Mixte de Recherche no. 5171 (UMR UM2 - IFREMER - CNRS), Université de Montpellier 2, 34095 Montpellier Cedex 5, France
²Laboratoire de Biométrie et Biologie Evolutive, Unité Mixte de Recherche n°5558 (UMR UCBL1 - CNRS), Université Claude Bernard-Lyon 1, 69622 Villeurbanne Cedex, France

Polymorphix is a database of intraspecific sequence polymorphism, structured under the ACNUC (http://pbil.univ-lyon1.fr/databases/acnuc/acnuc.html) sequence database management system. It allows one to select sets of within-(eukaryotic)species sequences families, and to visualize multiple alignments and phylogenetic trees. Polymorphix is useful for meta-analyses of population genomics, and as a bibliographic tool in population genetics. Families in Polymorphix are groups of sequences sharing at least 80% similarity. Multiple alignments were made with Mabios. Outgroup have been added when available (78% similarity required), and aligned to the within-species profile with Clustalv-1.81. Sequence alignments and Neighbour-Joining phylogenetic trees can be viewed. You can use them, together with sequence annotations and bibliographic links, to decide wether the selected families are relevant for your study.

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