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Polymorphix


NAR Molecular Biology Database Collection entry number 724
Bazin E.1, Duret L.2, Penel S.2, and Galtier N.1
1Laboratoire "GÉnome Populations Interactions Adaptation", UnitÉ Mixte de Recherche no. 5171 (UMR UM2 - IFREMER - CNRS), UniversitÉ de Montpellier 2, 34095 Montpellier Cedex 5, France
2Laboratoire de BiomÉtrie et Biologie Evolutive, UnitÉ Mixte de Recherche n°5558 (UMR UCBL1 - CNRS), UniversitÉ Claude Bernard-Lyon 1, 69622 Villeurbanne Cedex, France

Database Description

Polymorphix is a database of intraspecific sequence polymorphism, structured under the ACNUC (http://pbil.univ-lyon1.fr/databases/acnuc/acnuc.html) sequence database management system. It allows one to select sets of within-(eukaryotic)species sequences families, and to visualize multiple alignments and phylogenetic trees. Polymorphix is useful for meta-analyses of population genomics, and as a bibliographic tool in population genetics. Families in Polymorphix are groups of sequences sharing at least 80% similarity. Multiple alignments were made with Mabios. Outgroup have been added when available (78% similarity required), and aligned to the within-species profile with Clustalv-1.81. Sequence alignments and Neighbour-Joining phylogenetic trees can be viewed. You can use them, together with sequence annotations and bibliographic links, to decide wether the selected families are relevant for your study.


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