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HGNC Database


NAR Molecular Biology Database Collection entry number 73
Gray, K.A., Daugherty, L.C., Gordon, S.M., Seal, R.L., Wright, M.W. and Bruford, E.A.
HUGO Gene Nomenclature Committee (HGNC), Department of Biology, University College London, Wolfson House, 4 Stephenson Way, London NW1 2HE, UK

Database Description

Genew, the Human Gene Nomenclature Database, is the only resource that provides data for all human genes which have approved symbols. It is managed by the HUGO Gene Nomenclature Committee (HGNC) as a confidential database, containing over 16,000 records, 80% of which are represented on the Web by searchable text files. The data in Genew are highly curated by HGNC editors and gene records can be searched on the Web by symbol or name to directly retrieve information on gene symbol, gene name, cytogenetic location, OMIM number and PubMed ID. Data are integrated with other human gene databases e.g. GDB, LocusLink and SWISS-PROT and approved gene symbols are carefully co-ordinated with the Mouse Genome Database (MGD). Approved gene symbols are available for querying and browsing at: http://www.genenames.org

Recent Developments

The HUGO Gene Nomenclature Committee at the European Bioinformatics Institute has expanded largely owing to an increase in naming pseudogenes and non-coding RNA genes, and with now >33 500 approved symbols. Our gene families and groups have also increased to nearly 500, with about 45% of our gene entries associated to at least one family or group.

Acknowledgements

The HGNC is supported by The Wellcome Trust [081979/Z/07/Z] and [099129/Z/12/Z]; National Human Genome Research Institute [P41 HG03345].


Go to the abstract in the NAR 2008 Database Issue.
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