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YGOB


NAR Molecular Biology Database Collection entry number 791
Byrne K.P. and Wolfe K.H.
Department of Genetics, Smurfit Institute, University of Dublin, Trinity College, Dublin 2, Ireland.

Database Description

The Yeast Gene Order Browser (YGOB) is an online tool designed to facilitate the comparative genomic visualization and appraisal of synteny within and between the genomes of seven hemiascomycete yeast species. Three of these genomes are polyploid, and hence contain intra-genomic syntenic regions, the correct assembly of which is a particular success of YGOB. Designed to accurately assemble, display and score gene order relationships, YGOB is both an interactive tool for browsing genomic data, and a software engine that can be used for evolutionary analyses on a whole-genome scale. Underlying the online interface is the YGOB database, which consists of homology assignments across the species, extensively curated based on sequence similarity and novelly, an appraisal of genomic context (synteny) in multiple genomes. Version 1.0 of YGOB incorporates genome data from Saccharomyces cerevisiae, Candida glabrata, S. castellii, Ashbya gossypii, Kluyveromyces lactis, K. waltii and S. kluyveri, but the system is scaleable to accommodate additional genomes


Go to the abstract in the NAR 2006 Database Issue.
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