NAR Molecular Biology Database Collection entry number 808
Sierro N.1, Kusakabe T.2, Park K-J.1, Yamashita R.1, Kinoshita K.1,3 and Nakai K.1
1Human Genome Center, IMS, University of Tokyo
2Department of Life Science, Graduate School of Life Science, University of Hyogo
3Structure and Function of Biomolecules, SORST, JST

Database Description

Tunicates are lower chordates that include among others the two ascidians Ciona intestinalis and Ciona savignyi. This subphylum is particularly interesting because it shares many developmental and physiological characteristics, as well as basic gene repertoires, with vertebrates. The recent sequencing of two different Ciona genomes has lead to the identification of numerous genes. In order to better understand the regulation of these genes, DBTGR, a DataBase of Tunicate Gene Regulation, was created. It contains information on regulation of tunicate genes collected from literature, such as the minimal promoter length, the transcription factors involved and their binding sites or the localization of the gene expression, as well as binding sites for characterized transcription factors predicted based on published in vitro recognition sites. To allow identification of conserved cis elements, comparison of the promoters of homologous genes in both species is also provided.


This work was supported by a Grant-in Aid for Scientific Research from the Japan Society for the Promotion of Science (No. 17310114).

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