NAR Molecular Biology Database Collection entry number 85
Catalano D.1, Licciulli F.1, Grillo G.1, Turi A.1, Saccone C.1,2 and D'Elia D.1
1Istituto di Tecnologie Biomediche, Sezione di Bari, CNR, via Amendola 122/D, 70126 Bari, Italy
2Dipartimento di Biochimica e Biologia Molecolare, UniversitÀ di Bari, via Orabona, 4, 70126 Bari, Italy

Database Description

MitoRes [1] is an update of the MitoNuc database [2], extensively modified in its structure, data sources and graphical interface. MitoRes has been developed with the aim to provide a comprehensive, integrated and non-redundant resource for functional and comparative studies supporting research on basic science of mitochondria. The database contains data on nuclear-encoded mitochondrial proteins in Metazoa and provides comprehensive sequence datasets (gene, transcript and protein) as well as useful tools for their extraction and export. In addition, MitoRes clusters proteins on the basis of their sequence similarity and interconnects them with genomic data. A search engine and sequence management tools allow the query/retrieval of the database content and the extraction and export of sequences and related sub-sequences (intron, exon, UTR, CDS, signal peptide and gene flanking regions) ready to be used for in silico analysis.

Recent Developments

Changes recently introduced with respect to the last published version of the MitoNuc database have concerned (1) database structure, (2) data sources, (3) database content, (4) updating procedures (5) Web interface and (6) query/retrieval tool. More details are provided in the on-line Manual accessible by the database Home page.


This work has been supported by 'Ministero dell’Istruzione, dell’UniversitÀ e della Ricerca’ (MIUR), Italy, within the grants of PNR 2001-2003 (FIRB art.8) D.M. 199, Strategic Program: Post-genome, grant 31-063933; FIRB 2003 art. 8 D.D. 2187 del 12-12-2003 LIBI.


1. Catalano D, Licciulli F, Turi A, Grillo G, Saccone C, D'Elia D. MitoRes: a resource of nuclear-encoded mitochondrial genes and their products in Metazoa. BMC Bioinformatics, 2006 7:36
2. Attimonelli M, Catalano D, Gissi C, Grillo G, Licciulli F, Liuni S, Santamaria M, Pesole G, Saccone C. MitoNuc: a database of nuclear genes coding for mitochondrial proteins. Update 2002. Nucleic Acids Res. 2002, 30: 172-173

Go to the abstract in the NAR 2002 Database Issue.
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