ABA - Ascidian Body Atlas

NAR Molecular Biology Database Collection entry number 879
Hotta, K.1,2, Tahakashi, H.3, Ueno, N.3, Ikeo, K.1, Gojobori, T.1
1Center for Information Biology and DNA Data Bank of Japan, National Institute of Genetics, Yata 1111, Mishima, Shizuoka 411-8540, Japan
2Department of Biosciences and Informatics, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan
3Division of Morphogenesis, Developmental Biology Group, National Institute of Basic Biology, Okazaki 444-8585, Japan

Database Description

ABA (Ascidian Body Atlas) is a digital 3D atlas of ascidian embryo development and gene expression pattern. Our 3D embryo images were reconstructed from more than 3,000 high-resolution real images acquired by a confocal laser microscopy in different 30 developmental stages. Ascidian tadpole-type larvae consists of only 2600 cells that differentiated into similar tissues as vertebratesí one such as brain, nerve cord, notochord, endoderm, muscles. By using our database, we can follow each of cell lineages at one cell level from an egg to a larva. Our web-resource will be helpful for deciphering the molecular mechanism of the morphogenesis in the multi-cellular organism.

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