NAR Molecular Biology Database Collection entry number 904
Chen X.1, Wu J.-M.1, Hornischer K.2, Kel A.2 and Wingender E.2,3
1Centre of Bioinformatics, College of Life Sciences, National Laboratory of Protein Engineering and Plant Genetic Engineering, Peking University, Beijing 100871, China
2BIOBASE GmbH, Halchtersche Strasse 33, D-38304 Wolfenbüttel, Germany.
3Dept. of Bioinformatics, UKG, University of Göttingen, Goldschmidtstr. 1, D-37077 Göttingen, Germany

Database Description

TiProD is a database of human promoter sequences for which some functional features are known. It allows a user to query individual promoters and the expression pattern they mediate, gene expression signatures of individual tissues, and to retrieve sets of promoters according to their tissue-specific activity or according to individual GO-terms the corresponding genes are assigned to. We have defined a measure for tissue-specificity that allows the user to discriminate between ubiquitously and specifically expressed genes


This project was partially funded by Sino-German Center for Research Promotion (DFG & NFSC). We also would like to thank X. Gu, J. Luo, E. Shelest, and the members of the groups at PKU and UKG for helpful discussions. We are also indebted to K. Lennon-Hopkins for her linguistic advice.

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