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eSLDB - eukaryotic Subcellular Localization database


NAR Molecular Biology Database Collection entry number 930
Pierleoni A., Martelli P.L., Fariselli P. and Casadio R.
Biocomputing Group, University of Bologna, via Irnerio 42, 40126 Bologna, Italy

Database Description

eSLDB (eukaryotic Subcellular Localization DataBase) collects the annotations of subcellular localization of eukaryotic proteomes. For each sequence, the database lists localization obtained adopting three different approaches: 1) experimentally determined (when available); 2) homology based (when possible); 3) predicted. The latter is computed with a suite of machine learning based methods, developed in house. All the data are available at our website and can be searched by sequence, by protein code and/or by protein description. Furthermore a more complex search can be performed combining different search fields and keys. All the data contained in the database can be freely downloaded in flat file format.

Acknowledgements

RC acknowledges the receipt of the following grants: PNR 2001-2003 (FIRB art.8) for a project on Bioinformatics for Genomics and Proteomics, a FIRB 2003 LIBI-International Laboratory of Bioinformatics and the support to the Bologna node of the Biosapiens Network of Excellence project within the European Union’s VI Framework Programme (contract number LSHG-CT-2003-503265). PF acknowledges MIUR for a grant on Proteases. AP and PLM are supported by a FIRB 2003-LIBI grant.

References

1. Pierleoni A, Martelli PL, Fariselli P, Casadio R (2007) eSLDB: eukaryotic Subcellular Localization DataBase. Nucleic Acids Res. 35: in press


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