NAR Molecular Biology Database Collection entry number 961
Girard, L.1, Fiedler, T.3, Harris, T.3, Carvalho, F.4, Antoshechkin, I.1, Han, M.5, Sternberg, P.2, Stein, L.3 and Chalfie, M.6
1Division of Biology, 156-29, and 2Howard Hughes Medical Institute, California Institute of Technology, Pasadena, CA 91125, USA
3Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA
4Department of Pharmaceutical Sciences, St. John’s University, Queens, NY 11439, USA
5Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, CB10 1SA, UK
6Department of Biological Sciences, Columbia University, New York, NY 10027, USA

Database Description

WormBook (http://www.wormbook.org) is an open-access, online collection of original, peer-reviewed chapters on the biology of C. elegans and related nematodes. It contains over 100 chapters, covering nearly every aspect of C. elegans research, from cell biology and neurobiology to evolution and ecology. WormBook also contains WormMethods, a collection of methods and protocols used by nematode researchers. WormBook also serves as the text companion to WormBase, the C. elegans model organism database. Objects such as genes, proteins, and cells are linked to the relevant pages in WormBase, providing easily accessible background information. Additionally, WormBook chapters contain links to other relevant topics in WormBook, and the in-text citations are linked to their abstracts in PubMed and full-text references, if available.

Recent Developments

WormBook content continues to expand, with new chapters and sections broadening and elaborating on its scope. Since WormBook was launched in June 2005 with 12 chapters, it has grown to over 100 chapters. In addition to new topics, WormBook has also recently added several new features including Endnote compatibility and the option to download a zip file containing the entire contents of WormBook.


We thank the members of WormBase for helpful discussions and assistance. Funding for WormBook has been provided by the NIH (P41 HG02223), The Genetics Society, Society for Developmental Biology, as well as the generous support of the editors of C. elegans II.


1. Girard, L, Fiedler, T., Harris, T., Carvalho, F., Antoshechkin, I., Han, M., Sternberg, P., Stein, L., Chalfie, M. (2007) WormBook: the online review of C. elegans biology. Nucleic Acids Res. 35: in press.

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