Bacterial CSDB (BCSDB)

NAR Molecular Biology Database Collection entry number 977

Database Description

Bacterial Carbohydrate Structure Database (BCSDB) stores published data on glycans and glycoconjugates of bacterial and archaean origin. It provides data on structures, bibliography, taxonomy, 1H and 13C NMR spectrum assignment, methods used for structure elucidation, cross-references, and other information (medical, biosynthetic, etc.). As of 2015, it contains >10,900 glycan structures from >5900 organisms published in > 4400 articles, which covers nearly all bacterial glycans published up to 2013. Most data come from manual curation based on retrospective literature analysis. A part of structures published before 1996 was imported from the CarbBank database, appended with missing data and verified manually against the original publications with error correction. Main features of BCSDB are:

1) Regular updates aiming at high coverage, ca. 1000 new records are added annually;
2) High data quality achieved by automated and manual expert verification;
3) Manually verified bibliographic, taxonomic, and NMR spectroscopic annotations;
4) Automated data exchange with numerous other databases using dedicated formats and Resource Description Framework;
5) Freely available on the Internet
BCSDB is supplied with additional tools for empirical or database-driven 13C and 1H NMR spectrum simulation, NMR-based structure ranking, statistics on coverage and distribution of structural fragments among taxa, and clustering of taxa based on similarities in their glycans.


Subcategory: Carbohydrates

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