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PANTHER

NAR Web Server Collection entry number 11648
Contact   paul.thomas@sri.com

Description

Protein Analysis THrough Evolutionary Relationships (PANTHER) is a comprehensive software system for inferring the functions of genes based on their evolutionary relationships. Phylogenetic trees of gene families form the basis for PANTHER and these trees are annotated with ontology terms describing the evolution of gene function from ancestral to modern day genes. One of the main applications of PANTHER is in accurate prediction of the functions of uncharacterized genes, based on their evolutionary relationships to genes with functions known from experiment. The PANTHER website also includes software tools for analyzing genomic data relative to known and inferred gene functions.

Classification

Category: Protein
Subcategory: Databases

PubMed Abstract

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