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Why females live longer than males

1 December 2009

Researchers in Japan have found that female mice produced by using genetic material from two mothers but no father live significantly longer than mice with the normal mix of maternal and paternal genes. Their findings provide the first evidence that sperm genes may have a detrimental effect on lifespan in mammals. The research, which is published in Europe’s leading reproductive medicine journal Human Reproduction, found that mice created from two female genomes (bi-maternal (BM) mice) lived an average of 186 days longer than control mice created from the normal combination of a male and female genome. The average lifespan for the type of mice used in the study is between about 600-700 days, meaning that the BM mice lived approximately a third longer than normal.

Read the full article online here.

Published in Human Reproduction, Advance Access, 2 December 2009.

Read the full press release here.

In the news

The Times - How having two mothers may be the key to a longer lifespan

BBC - Men's genes may 'limit lifespan'

Telegraph - Men have a detrimental effect on lifespan

Daily Mail - Why women live so much longer than men