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Tricyclic anti-depressants linked to increased risk of heart disease

1 December 2010

Research that followed nearly 15,000 people in Scotland has shown that a class of older generation anti-depressant is linked to an increased risk of cardiovascular disease (CVD). The study showed that tricyclic anti-depressants were associated with a 35% increased risk of CVD, but that there was no increased risk with the newer anti-depressants such as the selective serotonin reuptake inhibitors (SSRIs). The study is published online today (Wednesday 1 December) in the European Heart Journal and was led by researchers from University College London (UCL).

Read the paper: Antidepressant medication use and future risk of cardiovascular disease: the Scottish Health Survey

Published in European Heart Journal, Advanced Access, 1 December 2010

Read the press release here.



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