SCOPE AND POLICY OF CARCINOGENESIS, INTEGRATIVE CANCER RESEARCH

Carcinogenesis is a multi-disciplinary journal that brings together all the varied aspects of research that will ultimately lead to the prevention of cancer in man. The journal will publish papers that warrant prompt publication in the areas of Cancer Biology (including the processes of promotion, progression, signal transduction, apoptosis, genomic instability, growth factors, cell and molecular biology, mutation, DNA repair, genetics etc), Molecular Epidemiology (including genetic predisposition to cancer and epidemiology), Cancer Prevention (including molecular dosimetry, chemoprevention, nutrition and cancer etc.) and Carcinogenesis (including viral, chemical and physical carcinogenesis, metabolism of carcinogens, and the formation, detection, identification and quantification of environmental carcinogens). The Editors may, from time to time, invite short reviews. Authors wishing to submit a review should contact one of the Editors before submission.

ETHICS

Carcinogenesis is a member of the Committee on Publication Ethics (COPE), and strives to adhere to its code of conduct and guidelines. Authors are encouraged to consult http://www.publicationethics.org.uk/guidelines for more information.

In reports of investigations in humans or animals, authors must explicitly indicate (in the appropriate section of the Methods) their adherence to ethical standards and note the approval of an ethics committee when this is relevant.

SUBMISSION OF MANUSCRIPTS

Carcinogenesis accepts submissions online http://mc.manuscriptcentral.com/carcin

For any queries please contact the editorial office:

Email:carcinogenesis.editorialoffice@oxfordjournals.org

Final accepted papers must be uploaded in a workable format NOT pdf files.

Please note: This journal does not accept Microsoft Word 2007 documents at this time. Please use Word's "Save As" option to save your document as an older (.doc) file type.

Submission of a paper implies that it reports unpublished work and that it is not under consideration for publication elsewhere. If previously published tables, illustrations or more than 200 words of text are to be included, then the copyright holder's written permission must be obtained. Copies of any such permission letters should be sent to the relevant Editor. Authors should identify the section in which they wish their paper to appear, i.e., Cancer Biology, Molecular Epidemiology, Cancer Prevention or Carcinogenesis, using the designated box within the Manuscript Data Sheet online. The online submission process also requires the author to provide the names and addresses of 3 or 4 potential referees.

Authorship: All persons designated as authors should qualify for authorship. The order of authorship should be a joint decision of the co-authors. Each author should have participated sufficiently in the work to take public responsibility for the content. Authorship credit should be based on substantial contribution to conception and design, execution, or analysis and interpretation of data. All authors should be involved in drafting the article or revising it critically for important intellectual content, and must have read and approved the final version of the manuscript. Assurance that all authors of the paper have fulfilled these criteria for authorship should be given in the covering letter.

PROOFS

Authors will be sent pdf proofs, it is imperative that a current email address is included for this purpose. To avoid delays in publication, proofs should be checked immediately for typographical errors and returned to the publishers by express (special delivery) post within 3 days. Alternatively, corrections may be sent via fax +44(0)1865 353773. Essential changes of an extensive nature may be made only by insertion of a Note added in proof. A charge will be made to authors who insist on amendment within the text at the page-proof stage.

PREPARATION OF MANUSCRIPTS

Manuscripts should be in their final form when they are submitted so that proofs will require only correction of typographical errors.

Sections of the manuscript
Regular full-length papers should be subdivided into the following sequence of sections: Title page, Abstract, Introduction, Materials and methods, Results, Discussion, Acknowledgements, References, Tables, Legends to Figures. In the journal the Materials and methods, Acknowledgements and References will be printed in smaller type to accommodate more text.

Authors should follow the below guidelines for manuscript length:

5000 words (excluding references and figure legends)
6 or fewer tables and/or figures (6 in total)
250 word limit for the abstract
~50 references

Submissions exceeding these guidelines may be returned unreviewed.

Supplementary Material
Only directly relevant material should be included in the full text of manuscripts. Supporting materials which are not essential in the full text, but would nevertheless benefit the reader, can be published as online-only supplementary data. Supplementary data should be submitted for review, in a separate file from the manuscript. Authors should ensure that supplementary data is referred to in the main manuscript at an appropriate point in the text.

LANGUAGE EDITING

Particularly if English is not your first language, before submitting your manuscript you may wish to have it edited for language. This is not a mandatory step, but may help to ensure that the academic content of your paper is fully understood by journal editors and reviewers. Language editing does not guarantee that your manuscript will be accepted for publication. If you would like information about one such service please click here. There are other specialist language editing companies that offer similar services and you can also use any of these. Authors are liable for all costs associated with such services.

GENERAL FORMAT

As referees may choose to print out your paper for reviewing purposes, all sections of the manuscript must be double-spaced with margins of 25mm (one inch) left at the sides, top and bottom of each page. Number each page top right (Title Page is 1). Please avoid footnotes, use instead, and as sparingly as possible, parenthesis within brackets.

ABSTRACT

The second page of every manuscript must contain only the Abstract, which should be a single paragraph not exceeding 250 words. Published papers will only have the first 250 words of their abstracts incorporated into Medline, text in excess of this limit will be lost. The Abstract should be comprehensible to readers before they have read the paper, and abbreviations and reference citations should be avoided.

ACKNOWLEDGEMENTS

These should be included at the end of the text and not in footnotes. Personal acknowledgements should precede those of institutions or agencies.

REFERENCES

Authors are responsible for the accuracy of the References. Published articles and those in press (state the journal which has accepted them) may be included. Arrange references in numerical order with the numbers in the text in brackets and on the line (not as superscripts). Note that all authors' names should be mentioned and the initials follow the name; the date should precede the title; the title should be given in full; the name of the journal should be abbreviated according to the World List of Scientific Periodicals and underlined to indicate italics. References should therefore be listed as follows:

• 1. Saffhill,R., Margison,G. and O'Connor,I. (1985) Mechanisms of carcinogenesis induced by alkylating agents. Biochim. Biophys. Acta, 823, 111-145.
• 2. Hatch,F.T., Felton,J.S., Stuermer,D.H. and Bjeldanes,L.F. (1984) Identification of mutagens from the cooking of food. In de Serres,F.J. (ed.) Chemical Mutagens: Principles and Methods for their Detection. Plenum Press, New York, vol. 9, pp. 111-164.
• 3. Bennett,M.V.L. and Spray,D.C. (1985) Gap Junctions. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.

Personal communications (J.Smith, personal communication) should be authorized by those involved, in writing, and unpublished data should be cited as (unpublished data). Both should be used as sparingly as possible and only when the unpublished data referred to is peripheral rather than central to the discussion. References to manuscripts in preparation, or submitted but not yet accepted, should be cited in the text as (B.Smith and N.Jones, in preparation) and should NOT be included in the list of references.

TABLES

Tables should be numbered consecutively with Roman numerals, they should be self-explanatory and include a brief descriptive title. Footnotes to tables indicated by lower case letters are acceptable, but they should not include extensive experimental detail. Please supply as rich text format or a word document not as a powerpoint attachment.

ILLUSTRATIONS

All illustrations (line drawings and photographs) should be referred to in the text as Figure 1 etc., abbreviated to 'Fig. 1.' only in the figure legend. Wherever possible, figures will be sized to fit the width of a single column of text, i.e., 88mm wide. The maximum width of a double column figure is 183mm, the maximum depth is 240mm. Figures with low density data will all be single column width. Please consider the overall page dimensions and layout, and the final reduction necessary for printing. Figures must be at a minimum resolution of 600 d.p.i. for line drawings (black and white) and 300 d.p.i. for colour or greyscare. Any lettering should be ~2mm in height in the printed figure (after reduction) and should be in proportion to the overall dimensions of the drawing. Labels should not be disproportionally large, and should show up clearly against the background.

PHOTOGRAPHS

Wherever possible, these must be submitted in the desired final size so that reduction can be avoided. Ideally, photographs should fit either a single column (88mm) or a double column (183mm). Photographs should be of sufficiently high quality with respect to detail, contrast and fineness of grain to withstand the inevitable loss of contrast and detail inherent in the printing process. Please indicate the magnification by a rule on the photographs.

COLOUR FIGURES

There is a special charge for the inclusion of colour figures. The cost is £350 per figure. (For cost purposes, the definition of a single figure is artwork that can be processed as a unit and printed on a single page without intervening type. Authors should note the potential cost savings inherent in this definition; for example, two consecutive half-page colour figures mounted as a composite and printed on one page, with both legends below or on the facing page, would be treated as one figure.) If there is a choice of colours on a schematic, please choose clearly distinct colours (e.g. not two shades of blue) and avoid black backgrounds if possible.

LINE DRAWINGS

Please provide clear, sharp prints, suitable for reproduction as submitted. No additional artwork, redrawing or typesetting will be done. Therefore, all labelling should preferably be made with a lettering set. Ensure that the size of lettering is in proportion with the overall dimensions of the drawing. Ideally, line drawings should be submitted in the desired final size to avoid reduction (maximum dimensions 248 x 185 mm including legends) and should fit either a single (88 mm) or a double column width (185 mm). If submitting line drawings which require reduction, please check that the lettering will be clearly legible after reduction to the size at which it will be printed. After reduction, letters should not be smaller than 1.5 mm in height.

FIGURE LEGENDS

These should be on a separate, numbered sheet. Define all symbols and abbreviations used in the figure. Common abbreviations and others in the preceding text should not be redefined in the legend.

CONVENTIONS

In general, the journal follows the conventions of the CBE Style Manual (Council of Biology Editors, Bethesda, MD, 1983, 5th edn).
Follow Chemical Abstracts and its indexes for chemical names. For guidance follow the recommendations issued by the IUPAC-IUB Commission on Bio-chemical Nomenclature, as given in Biochemical Nomenclature and Related Documents, published by the Biochemical Society, UK. For enzymes, use the recommended name assigned by the IUPAC-IUB Commission on Bio-chemical Nomenclature, 1978, as given in Enzyme Nomenclature, published by Academic Press, New York, 1980. Where possible, use recommended SI (Systeme International) units.
Genotypes should be italicized (underline in typed copy); phenotypes should not be italicized. For bacterial genetics nomenclature follow Demerec et al. (1966) Genetics, 54, 61-76.

ABBREVIATIONS

Restrict the use of abbreviations to SI symbols and those recommended by the IUPAC. Abbreviations should be defined in brackets after their first mention in the text. Standard units of measurements and chemical symbols of elements may be used without definition.

POLICY CONCERNING AVAILABILITY OF MATERIALS

It is understood that by publishing a paper in Carcinogenesis the authors agree to make freely available to colleagues in academic research any of the cells, nucleic acids, antibodies, animals etc. that were used in the research reported and that are not available from commercial suppliers.

LICENCE TO PUBLISH AND CONFLICT OF INTEREST

It is a condition of publication in the Journal that authors grant an exclusive licence to Oxford University Press. This ensures that requests from third parties to reproduce articles are handled efficiently and consistently and will also allow the article to be as widely disseminated as possible. In giving this exclusive licence, authors may use their own material in other publications provided that the Journal is notified and acknowledged as the original place of publication, and that Oxford University Press is notified in writing and in advance.

At the point of submission, Carcinogenesis Journal’s policy requires that each author reveal any financial interests or connections, direct or indirect, or other situations that might raise the question of bias in the work reported or the conclusions, implications, or opinions stated - including pertinent commercial or other sources of funding for the individual author(s) or for the associated department(s) or organization(s), personal relationships, or direct academic competition. When considering whether you should declare a conflicting interest or connection please consider the conflict of interest test: Is there any arrangement that would embarrass you or any of your co-authors if it was to emerge after publication and you had not declared it?

As an integral part of the online submission process, Corresponding authors are required to confirm whether they or their co-authors have any conflicts of interest to declare, and to provide details of these. If the Corresponding author is unable to confirm this information on behalf of all co-authors, the authors in question will then be required to submit a completed Conflict of Interest form to the Editorial Office. It is the Corresponding author’s responsibility to ensure that all authors adhere to this policy.

If the manuscript is published, Conflict of Interest information will be communicated in a statement in the published paper.

OFFPRINTS

The publishers supply a link to the paper's URL free of charge. Offprint order forms are sent out with the proofs, and must be returned with the proofs if extra offprints are required. Late orders submitted after the journal is printed are subject to increased prices.

Orders from the UK will be subject to a 15% VAT charge. For orders from elsewhere in the EU you or your institution should account for VAT by way of a reverse charge. Please provide us with your or your institution’s VAT number.

Carcinogenesis authors have the option, at an additional charge, to make their paper freely available online immediately upon publication, under the Oxford Open initiative. After your manuscript is accepted, as part of the mandatory licence form [http://www.oxfordjournals.org/our_journals/carcin/for_authors/licence.pdf ] required of all corresponding authors, you will be asked to indicate whether or not you wish to pay to have your paper made freely available immediately. If you do not select the Open Access option, your paper will be published with standard subscription-based access and you will not be charged.

For those selecting the Open Access option, the charges for Carcinogenesis vary depending on the institution at which the Corresponding author is based:

Optional Oxford Open charges:
For a Corresponding author based at an institution with an online subscription to Carcinogenesis:
Regular charge - £900 / $1800 / €1350
List B developing country charge** - £450 / $900 / €675
List A developing country charge** - £0 / $0 / €0

For a Corresponding author based at an institution that does not subscribe to the online journal:
Regular charge - £1500 / $3000 / €2250
List B developing country charge** - £750 / $1500 / €1125
List A developing country charge** - £0 /$0 / €0

*Visit http://www.oxfordjournals.org/jnls/devel/ for list of qualifying countries.

The above Open Access charges are in addition to any page charges and colour charges that might apply.

Orders from UK will be subject to a 17.5% VAT charge. For orders from the rest of the EU, we will assume that the service is provided for business purposes, please provide a VAT number for yourself or your institution and ensure you account for your own local VAT correctly.

If you choose the Open Access option you will also be asked to complete an Open Access charge form online. You will be automatically directed to the appropriate version of the form depending on whether you are based at an institution with an online subscription to Carcinogenesis. Therefore please make sure that you are using an institutional computer when accessing the form. To check whether you are based at a subscribing institution please use the Subscriber Test link for Carcinogenesis.

AUTHOR SELF-ARCHIVING/PUBLIC ACCESS POLICY FROM MAY 2005

For information about this journal's policy, please visit our Author Self-Archiving policy page.

FUNDING INFORMATION