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Thomas F. Lüscher
Bernard J. Gersh
Cardio NewsWire - archive
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The Cardio NewsWire site hosts highlighted news stories from the field of cardiology. This page holds an archive of previous stories published within the last 90 days, after this time stories are removed from the site.New EHJ Editors 2014
EHJ Today from AHA Dallas
Create a virtual patient
Davos Ultrasound Course
MOVD Symposium 2013
New - ESC Journals App
Heart and Brain Conference 2014
Hypertension in China
Obese women and stroke
Cardiovascular health and Brussels
Country of the Month
New Heart Failure Specialty Course
Best of ESC Congress 2013
New Cardiac iPhone / iPad App
ESC Cardiology Quiz at Amsterdam 2013
EHJ Top Reviewer and Editor 2012
NEW EHJ INTERNATIONAL ASSOCIATE EDITORS
David Celermajer and Ajay Shah join the EHJ Editorial team as International Associate Editors in 2014. From opposite sides of the globe they complement the editorial team with their expertise in different area.
Basic Science - the cell and molecular biology of atherosclerosis, especially endothelial adhesiveness and foam cell macrophage biology
Clinical research - mainly on non-invasive methods to assess arterial structure and function to detect early signs of vascular disease (especially endothelial dysfunction)
Public Health research in developing nations - collaborating on projects dealing with atherosclerosis in China and India; Rheumatic Heart Disease in Africa and Asia; and malaria-related vascular dysfunction in Indonesia
The role of redox signalling and NADPH oxidases in the pathophysiology of cardiac hypertrophy, and the roles of neuronal nitric oxide synthase (nNOS) in human cardiovascular regulation.
The British Heart Foundation Centre of Excellence led by Professor Shah focuses on enhancing interactions between cardiovascular and non-cardiovascular scientists, with particular efforts in imaging, biophysics, high resolution microscopy, proteomics and functional genomics. Major emphasis is also placed on research training for clinical and non-clinical scientists.
EHJ TODAY NEW INTERVIEWS FROM AHA DALLAS
Most recently, Executive Media Producer/ Managing Editor Sam Rogers and Amelia Meier, Managing Editor, produced 36 new interviews at the AHA Scientific Sessions 2013 in Dallas, with key members of the international cardiology community, Eugene Braunwald, Shahbudin H Rahimtoola, Valentin Fuster, Peter Libby, Marc Pfeffer and Bertram Pitt, amongst others.
The more than 250 interviews available on the EHJ website - covering a wide spectrum of topics in cardiology research - now effectively bolsters the EHJ's web presence - a fact amply reinforced by more than 67,000 visits this website feature has received so far.
CREATE YOUR OWN VIRTUAL PATIENT WITH CIRCADAPT SIMULATOR
Researchers from Maastricht University Medical Center released the CircAdapt Simulator. This freeware application enables you to simulate cardiovascular system dynamics in a wide variety of physiological and pathophysiological circumstances. The CircAdapt Simulator can now be downloaded free of charge from www.circadapt.org and is compatible with both Windows and Mac OS X.
The interactive CircAdapt Simulator simulates cardiovascular hemodynamics in real time. Dynamic tracings of blood pressures, volumes and blood flow velocities in the heart, blood vessels, valves and shunts, if present, are displayed graphically (Figure 1). This user-friendly application makes the complex dynamic behavior of the cardiovascular system accessible to a wide audience. The core of the CircAdapt Simulator is formed by the CircAdapt model of heart and circulation, which has been successfully used for basic research in cardiovascular (patho ) physiology during the last 10 years and partially funded by the Dutch Heart Foundation.
With the CircAdapt Simulator even a novice user can intuitively simulate complex pathophysiological situations by manipulating properties of heart valves, myocardial walls and blood vessels. For example, the hemodynamic consequences of a user-initiated mitral insufficiency can be evaluated and discussed (Figure 1). Its versatility makes the CircAdapt Simulator an ideal tool for teaching cardiovascular physiology and pathophysiology in a wide range of complexities. It may be used for teaching medical students, but also for more advanced training of residents in different clinical disciplines (e.g., cardiology, neonatology and intensive care medicine).
The developers from Maastricht University Medical Center (Figure 2) attach great importance to the spread of CircAdapt Simulator throughout the worldwide medical community. All requirements for incorporating CircAdapt Simulator in medical schools and elsewhere will be available as freeware on the website www.circadapt.org. The website is envisioned to become an open platform where users can discuss and exchange ideas and materials related to CircAdapt. The team’s intention is that more and more students, scientists and clinical specialists will benefit from CircAdapt.
A more detailed report of the CircAdapt project will appear in CardioPulse in February 2014.
Figure 1: Graphical impression of the CircAdapt Simulator showing tracings of blood pressures, ventricular cavity volumes, and blood flow velocities in normal, healthy circumstances (REFERENCE) and during 10% MITRAL INSUFFICIENCY.
Figure 2: CircAdapt research team members (from left to right): Joost Lumens, PhD, Tammo Delhaas, MD, PhD, Koen Reesink, PhD, Theo Arts, PhD, and Willem Dassen, PhD.
INTERNATIONAL CONGRESS ON ADVANCES IN CARDIAC ULTRASOUND
State-of-the-art lectures will provide cardiologists and those interested in cardiac ultrasound a review of all current clinical challenges and new developments and how to implement them in daily practice. Particular emphasis will be on quantitative Doppler haemodynamics, state-of-the-art 3D and 4D echocardiography, the role of echo in arrhythmias, diastology, and how to assess valve regurgitation in the 21st century as well as echo in emergencies and other important clinical scenarios.
Lectures will be delivered by high quality international masters of echocardiography including Jo Kisslo (USA), Itzhak Kronzon (USA), Fausto Pinto (Portugal), Patrizio Lancellotti (Belgium), Francesco Faletra (Switzerland), Joachim Nesser (Austria), Raphael Rosenhek (Austria), Mark Monaghan, Roxy Senior and Mike Bellamy from the UK.
The course is known for the extensive discussions and interactions between participants and faculty and is supported by the European Association of Cardiovascular Imaging.
The course takes place in the city of Davos, one of the most spectacular locations in Europe. The city is the highest in Europe, situated at 1560 meters above sea level. It is renowned for hosting the annual World Economic Forum as well as many other medical meetings in its impressive Conference Centre.
We both look forward to seeing you in Davos 2014!
Jeroen J. Bax (L) and Petros Nihoyannopoulos (R) credit Sam Rogers
For further information on the course and programme please visit us online www.regonline.co.uk/davos2014
Tel: +44 (0)20 3313 1606
Contact: Tony Steedman, Conference Manager
11TH INTERNATIONAL SYMPOSIUM ON MECHANISMS OF VASODILATION
Topic categories were:
The Sympathetic System in Hypertension and Heart Failure with Professor Murray Esler from Melbourne, Australia giving the John T. Shepherd Lecture.
Novel Vasoactive Peptides: David Bohr Lecture held by Clinton R. Webb from Augusta, USA who spoke about “Mitochondria-derived Peptides: Novel Mediators of Vasodilation”. Of note, mitochondria contain N-formyl peptides activating specific receptors leading to profound vasodilatation. Such a mechanism appears to be particularly important in septic shock and the discovery of this pathway, which is inhibited by cyclosporine-H, is likely to provide novel opportunities to treat this devastating condition, which still has a mortality rate of 30 to 50%.
Vascular Adaptation in Hypertension: Ernesto L. Schriffrin, an eminent clinician and hypertension researcher from Montreal, Canada had been invited to give the Björn Folkow Lecture on growth and remodeling. He spoke on the “Effects of Immune Mechanisms on the Vasculature in Hypertension”.
Endothelial Function in the Cerebral Circulation: Zvonimir S. Katusic, Mayo Clinic, USA gave the 4th Paul M. Vanhoutte Lecture on vascular pathology. His lecture on “Endothelial Nitric Oxide in Cerebrovascular Disease” revealed truly novel aspects of the role of nitric oxide in Alzheimer disease.
Other speakers included: Uta Hoppe, Paracelcus Medical University Salzburg, Austria, Christian Templin, University Hospital Zurich, Switzerland, Felix Mahfoud, Homburg, Germany, Mario Bigazzi, Prosperius University, Florence, Italy, Marco Metra, University of Brescia, Italy, Stefan Anker, Berlin, Germany,
More details of presentations in CardioPulse, EHJ issue 35/03.
NEW! ESC JOURNALS APP FOR ALL ESC JOURNALS
The new ESC Journals App now includes all ESC owned Journals. Get it here.
The ESC Journals App from Oxford University Press brings the ESC's leading cardiology journals both online and offline – free for a limited time to non-subscribers – to iPad, iPhone, or iPod Touch.
- Intuitively and quickly navigate journal articles, figures, and tables-
- Use the built-in search feature
- Save the most relevant articles to your favourites
- Automatically download issues and articles when you’re online, so that you can read them whether you’re connected to the Internet or not.
Three more journals have been added to the App in version 4.1, so now, 9 of the world’s leading cardiology journals can be accessed on iPad, iPhone, or iPod Touch. Bugs have been fixed and some advertising has been included.
The ESC represents over 80,000 cardiology professionals, principally from across Europe and the Mediterranean basin, but also from the rest of the world.
HEART AND BRAIN CONFERENCE 2014
The second ICHB will take place in Paris, France 27 Feb-1 March 2014
Expert neurologists and cardiologists will explore the essential connection between cardiovascular health and brain function, presenting state-of-the-art research and breakthroughs.
In recent years abundant new data has been accumulated on the relationship between the heart and the brain and vice versa. New therapies continue to be developed and it is time for cardiologists and neurologists to talk together, to learn from each other, discuss and exchange ideas and benefit from one another’s expertise. The scientific programme is designed to bring all news from these two fields together into one place, to facilitate this exchange of knowledge.
o Atherosclerosis: CAD & Aorta
o Atrial Fibrillation
o Cognition & the Heart
o Endocarditis and uncommon Cardiac Sources of Embolism
o Revascularization in stable Atherosclerosis
o Stress, the Brain, and the Heart
o The Bleeding Brain: Haemorrhagic Complications: What Have We Learned
o Vascular Neurology for the Cardiologist: The Device Era in Vascular Neurology
o Aortic Arch Atherosclerosis
o Aortic Dissection and Stroke
o Atherosclerosis of Proximal Cerebral Vessels
o Atrial Fibrillation
o Basic Science
o CABG: Risk and Prevention of Cerebral Embolism and/or Cognitive Impairment
o Cognition & the Heart
o Disease in TIA/Stroke Patients
o Heart Failure
o Ischemic Heart Disease as a Source of Cerebral Embolism
o New Diagnosis Methods/Devices
o PCI, Antithrombotic Treatment and the Risk of Stroke in ACS Patients
o Prevalence and Risk of Coronary Artery
o Stress - Effect on the Heart and Brain
o Stroke of Unknown Cause and the Heart
o TAVI, PFO, BRAKT, LAA
o The Cardiac Patient at Risk for Stroke
o The Effect of acute Brain Ischemia on the Heart
o Vascular Neurology for the Cardiologist
The Core Scientific Committee
Philippe Gabriel Steg
HYPERTENSION IN CHINA HIGH ON CONGRESS AGENDA
The ESC presented a full programme at the meeting, including discussion of the latest European Guidelines on Hypertension. When current treatment guidelines are followed, BP can be successfully controlled in up to 84% of cases, according to a new Chinese study that was presented at the recent ESC Congress 2013 in Amsterdam.
Despite this, the WHO report shows that more than 40% of Chinese people with HTN are unaware of their condition, about 50% are receiving no medication, and about 80% are not controlling it well.
Dayi Hu, MD, President of the Chinese Congress of Cardiology, said the GW-ICC & APHC expected over 13,000 delegates from across 30 regions and countries and is now the largest cardiology congress in the Asia Pacific region.
YOUNG OBESE WOMEN CAN REDUCE STROKE RISK
Risk of stroke increases 3.5 times in young women who are overweight or obese and have metabolic disorders.
Of the 15 million people who experience a stroke each year, six million do not survive. Worldwide about 30 million people have had a stroke and most have residual disabilities.
Recent data published in the Lancet, shows a striking 25% increase in the number of stroke cases in people aged 20 to 64, worldwide (1). This younger age group now accounts for 31% of stroke cases (up from 25% before 1990).
References 1) The Lancet Global Health: http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)61953-4/abstract
CARDIOVASCULAR HEALTH TAKES CENTRE STAGE IN BRUSSELS
During the week MEP Heart Group meetings will be held with European experts to discuss pressing issues related to cardiovascular health. Other activities include cardiopulmonary resuscitation (CPR) training, free cardio fitness classes in the European Parliament Sports Centre, and heart healthy meals in the main European Parliament restaurant.
In addition, a cardiovascular screening exercise will allow MEPs to have their BP and cholesterol measurements taken, to predict their 10-year risk of mortality from heart attack and stroke. They will then receive advice on how to adopt a more heart healthy lifestyle. Staffan Josephson, President of the European Heart Network, said: "We hope this will show MEPs that there is a lot they can do to help protect EU citizens if CVD-friendly policies are in place, such as banning smoking in public places and making healthy food affordable".
Cardiovascular Health Week kicks off with an Opening Ceremony which will be attended by high-level keynote speakers including the European Commissioner for Health Tonio Borg, Lithuanian Minister of Health Dr Vytenis Povilas Andriukaitis, and Dr Roberto Bertollini, Chief Scientist and World Health Organization Representative to the EU.
Warmly welcoming the initiative, Tonio Borg, said: “As the primary cause of death and disability in Europe, cardiovascular diseases deserve great attention at EU level. This awareness week is a big step towards putting CVD higher on the EU agenda and generating an environment that is conducive to cardiovascular health, for the good of European citizens”.
EACPR INITIATES COUNTRY OF THE MONTH SERIES
(i) To inform the broader European cardiology community about the state of prevention in the different countries
(ii) To facilitate communication and mutual support within the network of national CVD prevention coordinators.
On the CoM page there is an interactive map, that will be filled with 2 new countries every second month. Clicking on the country will provide the contact data of the national cardiovascular disease (CVD) prevention coordinator and a link to the report. The report contains a short summary (3-5 minutes to read) and links to more detailed information on different topics, including links to relevant sites, projects and publications.
Stephan Gielen, EACPR President stated “There are so many good prevention initiatives around Europe that they deserve greater interest; therefore we believe the EACPR CoM page can develop into a main European source for spreading information”!
A NEW POSTGRADUATE COURSE FOR HEART FAILURE MANAGEMENT
A course specifically designed for the heart failure specialist begins in 2014. It is based on the new curriculum of the ESC Heart Failure Association and is certified by the European Society of Cardiology. The course will be held in Zurich and Brussels from January 2014 to October 2015.
The objective is to produce a cardiologist not only competent in clinical medicine and pharmacotherapy, but also knowledgeable about cardiac devices and their programming, imaging of the heart, and detection of dyssynchrony.
Doctors will also be informed of the indications for other procedures in the coronary circulation and the valvular apparatus and the management of patients before and after heart transplantation.
The course will take place on Thursday to Saturday and consist of 8 modules each of 2.5 days. There will be 20 hours of structured learning per week (160 hours total) and 140 hours of self-study.
Modules 1-5 and 7-9 will be held at the University Hospital Zurich, Switzerland and module 6 at ESC Headquarters Brussels, Belgium.
Final examinations will result in a European Medical Certificate of the ESC and a Certificate of Advanced Studies (CAS) by the University of Zurich.
Programme Director: Kirsten Schlaudraff MD email@example.com
Deadline for application is 15 November 2013.
BEST OF ESC CONGRESS 2013
Some of the most important studies presented at ESC Congress 2013, according to Prof Fox were:
• HOKUSAI-VTE: The oral anticoagulant edoxaban for the treatment of venous thromboembolism (VTE) resulted in equal efficacy and better safety compared to standard warfarin, when either drug was used with initial low molecular weight heparin (LMWH)
• TASTE: The aspiration of the blood clot or “thrombus” that causes a heart attack before re-opening a patient’s artery with a balloon catheter does not improve survival compared to performing balloon dilation and stenting alone
• REALIGN: Results reaffirm current guidelines excluding patients with a narrow QRS for CRT, and expand the body of evidence that simple electrocardiographic determination of QRS duration remains the most important predictor of the clinical benefits of CRT, rather than measures of mechanical dyssynchrony by echocardiography. Based on the results of EchoCRT, the identification of patients who will obtain the benefit of CRT can be done most easily by a 12 lead-ECG.
• DECAAF: Results showed that in patients with atrial fibrillation, delayed enhancement magnetic resonance imaging (DE-MRI) performed before ablative treatment can stage the degree of damaged heart tissue (atrial fibrosis) and help predict whether treatment will be successful or not.
• PRAMI: Heart attack patients with ST elevation who undergo a preventive procedure to unblock additional coronary arteries have significantly better outcomes than those whose treatment is confined to the culprit blockage only.
“These studies will influence clinical practice and will allow us to better understand how to manage these important conditions and how to devise even newer therapies,” explained Prof Fox.
Earlier this year the ESC and its sponsors published a White Paper on the state of research and development in cardiology calling for urgent investment in CVD innovation. With a growing ageing population and increase of cardio metabolic diseases, doctors are expecting the incidence of CVD to rise in the future. “Studies such as PURE and EUROASPIRE IV confirm these differences and also the need to strive for better and equal access of patients in all countries to better prevention programmes, to the best treatment and also rehabilitation.” Prof Vardas concluded.
Some of the most popular “stories” with the wide range of media covering the event from Amsterdam were: • The Tour de France study demonstrating that French participants in the race between 1947–2012 lived longer than their same-age French counterparts
• Listening to music that makes you happy and relaxed alone and in addition to regular exercise training, improves endothelial function (by releasing endorphins)
• Cold weather is by far the most important environmental trigger for myocardial infarction whereas air pollution has a lesser effect
• Statins show a protective effect preventing cataracts, the leading cause of visual impairment worldwide affecting more than 20 million people
Prof Fox concluded: “It was great to see hundreds of doctors cycling to the Congress centre in the morning. Let’s just hope that their example will help drive home the importance of exercise to live a long and healthy life, even if we cannot emulate our Tour de France heroes!”
CARDIAC ARRHYTHMIA CHALLENGE
Unique iPhone / iPad application now released, for case-based self-assessment in cardiac arrhythmias
Continuing medical education for cardiac arrhythmias and invasive electrophysiology (EP) has long been problematic, due to the sophisticated setup of the EP lab. Additionally, different modalities involved in real-life patient cases all have to be evaluated together, in order to come up with the correct solution for a specific problem. Indeed, long EP tracings, 12 lead ECGs, information from 3D mapping systems and fluoroscopy images are often needed to comprehensively assess a specific case, which is difficult, if not impossible, by conventional teaching methods such as textbooks.
Jan Steffel MD (consultant electrophysiologists and cardiac device specialist, Department of Cardiology, University Hospital Zurich) and Gerhard Hindricks MD (Director of Electrophysiology, University Heart Center Leipzig) have now tackled just this issue. Their iPhone / iPad App “Cardiac Arrhythmia Challenge” allows users to assess their knowledge and skills in 50 case-based questions regarding clinical arrhythmology, as well as invasive electrophysiology.
In contrast to conventional text books, the app provides all the material encountered in daily clinical practice to assess a problem and find the solution, including standard 12-lead ECGs, invasive EP tracings, 3D mapping images, radiographs, fluoroscopy images and / or other features (if available). In addition, the user – as in real life – is able to scroll ECGs and EP tracings, and can zoom these and other objects (such as 3D mapping images) for better visibility of even subtle signals and details. The app is a successor to the successful “Cardiac Device Challenge” App, released just last year and covered by EHJ Newswire, which deals with device related cases comprising similar features.
According to the authors, both apps should be “of great value and fun” not only for board certified cardiologists and electrophysiologists, but also for cardiologists in training and other healthcare professionals who wish to review and increase their knowledge and skills of cardiac arrhythmias. Currently, the app contains 50 questions - with many more to follow, according to the authors.
The App is available at the iTunes Store.
For further information visit www.corxl.com
ESC CARDIOLOGY QUIZ AT ESC CONGRESS 2013
Swiss team defeated by newcomers from Moscow
The Quiz is designed as a new learning and educational tool with 3 competing teams and a “Supreme Court” of three leaders in cardiology.
This year’s Judges were:
Miss Victoria Buziashvili Professor Victoria Ioshina Dr Dzhamshed Kamardinov Dr Maxim Mamalyga Professor Simon Matskeplishvili
More details of the event will be in CardioPulse EHJ issue 34-41(29 October 2013). The ESC looks forward to seeing the Russian champions defending their cup next year, 2014, in Barcelona.
TOP EHJ REVIEWER AND EDITOR OF THE YEAR 2012
At the Annual Congress of the European Society of Cardiology, the European Heart Journal traditionally organizes a well-attended editorial board meeting. Indeed, this year in Amsterdam, 3 September 2013, editors and reviewers participated. The editor-in-chief Thomas F. Lüscher reported on the progress of the journal including the number of submitted papers, the acceptance rates and the impressive growth in the Impact Factor and outlined the future course of the journal. He stressed the importance of excellent and knowledgeable reviewers as a key success-factor for the European Heart Journal. As every year, the editor-in-chief was therefore proud to announce the Top Reviewer for 2012 Professor Johann Auer, and to honour the 20 best performing reviewers.
Top Editors Filippo Crea, left, and Stefano Taddei, right, credit Sam Rogers
Open access options for authors visit Oxford Open