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Thomas F. Lüscher
Bernard J. Gersh
Cardio NewsWire - archive
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The Cardio NewsWire site hosts highlighted news stories from the field of cardiology. This page holds an archive of previous stories published within the last 90 days, after this time stories are removed from the site.Cardiac benefits of alcohol questioned
A new ablation catheter
ACCA certification exam
Aortic stenosis patients 1 year after intervention
Russian National Congress of Cardiology
AHA statement on evaluation of women with suspected IHD
New ACCA Research Prize in 2014
Acute Cardiovascular Care 2014
Ethica Award 2014 to Adnan Kastrati
Periodontal disease a cardiovascular risk factor?
HEART HEALTH BENEFITS OF LIGHT DRINKING QUESTIONED
A reduction in alcohol consumption, even for light-to-moderate drinkers, could be linked to improved cardiovascular health, including a reduced risk of coronary heart disease, lower body mass index and blood pressure, according to new research published in The BMJ (1).
These latest findings challenge the results of previous observational studies which found that the consumption of light-to-moderate amounts of alcohol (12-25 units per week) may have a protective effect on cardiovascular health.
The research, led by the London School of Hygiene & Tropical Medicine with University College London and University of Pennsylvania, looked at evidence from over 50 studies into the drinking habits and cardiovascular health of over 260,000 people. They found that individuals who carry a genetic variant which tends to lower their alcohol consumption have, on average, a more favourable cardiovascular profile. The authors say this suggests that a reduction in alcohol consumption, even for light-to-moderate drinkers, is beneficial for cardiovascular health.
Specifically, the researchers found that these individuals had on average a 10% lower risk of having coronary heart disease, lower blood pressure and a lower Body Mass Index.
Previous observational studies are also limited by the issue of distinguishing between self-reported non-drinkers, who may include those who have never consumed alcohol, and those who consumed alcohol in the past but have since stopped as a result of ill-health. Issues like these make it difficult for observational studies to assess the health effects of long-term alcohol consumption levels.
The current study’s results strongly suggest that reduction of alcohol consumption is beneficial for cardiovascular health, and is closer to establishing causality than observational studies, however further replication of similar genetic studies using large-scale prospective studies, such as the UK Biobank, will be needed.
The study was funded by the British Heart Foundation and the Medical Research Council and was an international collaboration that included 155 investigators from the UK, continental Europe, North America, and Australasia.
Reference 1. Paper reference: Michael V Holmes, Caroline E Dale et al. Association between alcohol and cardiovascular disease: mendelian randomisation analysis based on individual participant data. The BMJ. DOI: 10.1136/bmj.g4164 Link to paper: http://www.bmj.com/content/349/bmj.g4164
FLEXABILITY ABLATION CATHETER APPROVED
The FlexAbility™ Ablation Catheter from St Jude Medical received CE Mark approval at the end of July 2014.
The catheter combines an irrigated flexible catheter tip with a state-of-the-art handle and catheter design. The next-generation flexible tip technology was designed to help reduce complications associated with ablation procedures through its ability to bend and conform to the cardiac anatomy, decreasing the amount of pressure distributed to a patient’s endocardium while simultaneously increasing the stability of therapy delivery.
The FlexAbility catheter features an innovative handle and shaft that allows for improved manoeuvrability. The technology was designed to provide optimal irrigation flow over the entire tip for improved cooling. The first cases that used the FlexAbility catheter after approval took place at IdealMed Unidade Hospitalar de Coimbra in Coimbra, Portugal by Dr. Andrea Natale and at the Hôpital Haut-Lévèque in Bordeaux, France by Dr. Nicolas Derval.
Data produced by the FlexAbility ablation catheter are displayed on the EnSite™ Velocity System™, a cardiac mapping and navigation system. Once FlexAbility catheters are inserted in the cardiac chamber the EnSite system records electrical information from the heart and displays it in a three-dimensional anatomical model.
Another catheter, The TactiCath™ contact-force sensing irrigating ablation catheter is designed to give physicians a real-time, objective measure of the force applied to the heart wall during a cardiac ablation procedure and has been available in Europe since 2012.
The TactiCath catheter and FlexAbility ablation catheters are investigational devices in the United States.
REGISTRATION FOR ACCA EXAM NOW OPEN
The Certification process on Acute Cardiac Care has been designed to train professionals to deliver state of the art treatment for patients with severe cardiac illnesses. This process is composed of two parts: the written exam and the logbook part.
To prepare for the certification programme, a ‘How to’ session will take place during the Acute Cardiovascular Care congress immediately before the exam at 08:30 - 09:30 on 20 October.
Online registration for the examination is now open until 13 October 2014.
More information is available at:
PATIENTS ARE THE SAME OR BETTER 1 YEAR AFTER AS INTERVENTION
A survey, published online in the European Journal of Cardio-Thoracic Surgery, of 13,860 patients who had undergone interventions for aortic valve disease in Germany has revealed that over 80% were in the same or a better state of health one year after the intervention, and were satisfied with the procedural outcome.
One-year mortality was 6.7% (6,523) for conventional AVR patients and 11% (3,464) for patients who underwent AVR with CABG. One-year mortality 20.7% and 28% in transvascular TAVR and transapical TAVR procedures respectively. However, if patients were stratified into four risk groups, the highest-risk cohorts showed the same mortality at one year regardless of type of therapy.
Prof. Mohr said: “GARY is unique in that it includes all interventional and surgical treatment options for aortic valve disease that are currently available in Germany. Our aim was to obtain a comprehensive and contemporary picture of the current practice of aortic valve intervention therapy and to create an independent database that will allow for long-term follow-up of those patients.”
“The one-year results of the German Aortic Valve Registry confirm in a large ‘real world’, all-comer patient population that conventional surgery in operable patients’ yields excellent results in all risk groups. TAVR is being performed in a significant proportion of cases and is a good alternative for high-risk patients. Continuation of the registry and long-term follow-up will help to develop robust future risk models to predict patient outcomes for each treatment option in patients with aortic stenosis.”
RUSSIAN NATIONAL CONGRESS OF CARDIOLOGY
The Congress scientific programme will include the most prominent modern achievements in prevention, diagnostics and treatment of cardiovascular diseases. An interdisciplinary approach to the problems is of exceptional value, as it fully represents the current trend to integrate knowledge in medical science. No less important is a strong educational component of plenary sessions, symposia, clinical discussions, scientific seminars, round tables, and master classes.
• Improvement in Cardiology Care
• Fundamental Research
• New Medical Technologies
• Pharmacotherapy of Cardiovascular Diseases
• Congenital Cardiovascular Disorders
• Pulmonary Circulation Disorders
• Diabetes Mellitus and Cardiovascular Diseases
• Comorbidity in Cardiology
• Cardiac Problems in Perinatology and Paediatrics • Interventional Cardiology
• Surgical Methods in Cardiology
• Heart Transplantation
• Cardiac Rehabilitation
• Prevention of Cardiovascular Diseases
• Nursery Care Organization
The scientific program includes keynote lectures, plenary sessions, scientific symposiums, workshops, poster sessions, a Young Cardiologist Award session, as well as training sessions for practicing doctors.
During the Congress, the Russian Society of Cardiology Prize awarding ceremony will take place.
The final scientific program will be available at: www.scardio.ru 2 months prior to the event.
AHA STATEMENT ON EVALUATION OF WOMEN WITH SUSPECTED IHD
The American Heart Association (AHA) has published a statement on diagnostic testing for suspected ischaemic heart disease (IHD) in symptomatic women. The statement focuses on identifying non-obstructive and obstructive coronary artery disease (CAD).
Sex specific data are provided on the diagnostic and prognostic accuracy of numerous tests including exercise treadmill, ECG, stress echocardiography and stress cardiac MRI.
Gaps in knowledge about the assessment of IHD risk in women are identified.
The statement says that women are more likely than men to be diagnosed with non-obstructive coronary heart disease. Women previously diagnosed as having false positive stress tests may have non-obstructive coronary disease, placing them at risk for myocardial infarction. The statement is intended for women who have the symptoms of IHD, including the classic symptoms of left sided chest pain/pressure, jaw pain, upper back pain, widespread “indigestion,” and other symptoms not localised to the chest.
• Women with suspected IHD should discuss the benefits and risks of diagnostic tests with their healthcare provider – for example, a woman of child-bearing age may want to avoid tests that require exposure to radiation
• Healthcare professionals should consider whether a woman is at low, intermediate, or high risk for IHD when choosing the appropriate diagnostic tests
• Health care professionals, for the first time, should consider a woman’s functional ability to determine the type of diagnostic testing needed
• Women with the lowest risk should not undergo diagnostic testing; women at slightly higher risk should first undergo a treadmill exercise ECG; and symptomatic women with warning signs, including functional disability, might be candidates for cardiac MRI or cardiac CT angiography.
The document was published online on 16 June 2014
NEW IN 2014: ACCA RESEARCH PRIZE
Acute Cardiovascular Care 2014 takes place 18-20 October 2014 in Geneva, Switzerland.
ACC 2014 THEME: THE HIGHLY VULNERABLE PATIENT
This year's theme is The Highly Vulnerable Patient, and the Congress Committee has carefully constructed a programme that is rich in educational and state of the art content. Here are a few highlights from the scientific programme, not to be missed:
• NEW! Sceptic's Corner
• The vulnerable STEMI patient
• Cooling after out of hospital cardiac arrest
• Pre-hospital diagnosis and management of cardiac emergencies
• NEW! First Aid for lay people, a joint session with the International Federation of Red Cross and Red Crescent Societies
• Emergent situations in patients on new oral anticoagulants
• NEW! Hotline Session - Submission will soon be open for researchers wishing to present their latest clinical trials and research.
ADNAN KASTRATI RECEIVES ETHICA AWARD 2014
Each year the EuroPCR Board recognises an outstanding physician for their contribution to cardiovascular intervention as teacher, scientist, care provider or pioneer with the presentation of the Ethica Award.
In his research, Kastrati has focussed on optimising treatment strategies in patients with acute coronary syndrome and developing new drug-coated stents with improved safety and efficacy profile. He has also explored the optimisation of adjunctive peri-procedural antithrombotic therapy and the evaluation of prognosis based on genetic and biochemical markers.
Adnan Kastrati is currently Professor of Cardiology and Head of the Catheterization Laboratory at Deutsches Herzzentrum, and Director of the ISAR Research Centre, Munich, Germany.
Accepting the award Kastrati said, “I see this award not only for me, but the whole ISAR team. It has been a great time to work with all these people”.
Periodontal disease associated with cardiovascular risk in large multicentre study
Should dental health now be considered a marker of coronary heart disease?
Periodontal disorders such as tooth loss and gingivitis have been identified as a potential risk marker for cardiovascular disease in a large study published by the European Journal of Preventive Cardiology (1).
More than 15,000 patients with chronic coronary heart disease provided information on their dental health, with results showing that indicators of periodontal disease (fewer remaining teeth, gum bleeding) were common in this patient group and associated with numerous cardiovascular and socioeconomic risk factors.
Conversely, a lower prevalence of tooth loss was associated with lower levels of CVD risk factors, including lower glucose levels, low-density lipoprotein cholesterol levels, systolic blood pressure, and waist circumference. Diabetes and smoking were also less prevalent among patients with more teeth, while the likelihood of higher education, alcohol consumption and work stress was greater.
The report, published in the European Journal of Preventive Cardiology, summarised information on self-reported dental health from the STABILITY trial, a clinical trial involving 15,828 participants from 39 countries all with chronic coronary heart disease and at least one additional risk factor for CHD. This, say the authors, is the largest study of its kind to assess dental disease in coronary patients, and demonstrates a heavier burden of CVD risk factors and higher levels of biomarkers among those with more tooth loss and gum bleeding, even after adjusting for confounders (such as age, smoking, diabetes and education level). The findings suggest common risk factors for dental disease and coronary heart disease, and raise the question of whether self-described dental health can now be considered a useful marker of CVD risk.
1. Vedin O, Hagström E, Gallup D, et al. Periodontal disease in patients with chronic coronary heart disease: Prevalence and association with cardiovascular risk factors. Eur J Prevent Cardiol 2014; DOI: 10.1177/2047487314530660
THIRD JOINT MEETING FOR MICROCIRCULATION
The third Joint Meeting of the German Society for Microcirculation and Vascular Biology (GfMVB) and the Swiss Society for Microcirculation and Vascular Research (SSMVR) will take place from 30 September – 2 October 2014 in Münster, Germany.
The deadline for abstract submission is on 30 June, 2014
Furthermore there will be the Young Investigator Award Session.
The Hermann-Rein Prize 2014 will be awarded during the 3rd Joint Meeting. Please note the deadline of July 1, 2014 for the Hermann-Rein Prize submissions.
For more details please visit the following link: http://www.microcirculation-conference.de
Open access options for authors visit Oxford Open