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December 6, 2013

Decreased Diversity of the Bacteria Microbiome in the Gut is Associated With Risk of Colorectal Cancer Decreased diversity in the microbial community found in the human gut is associated with colorectal cancer.

October 9, 2013

New Technique Allows Anti-Breast Cancer Drugs to Cross Blood-Brain Barrier Some breast cancer drugs can penetrate the blood-brain barrier (BBB), but they have not been very effective against brain metastases, whereas other, more effective anti-breast cancer drugs cannot penetrate the BBB at all.

September 19, 2013

Proteins that Deliver Leucine to Prostate Cancer Cells Are Therapeutic Targets Like normal cells, cancer cells require amino acids for growth, maintenance, and cell signalling, and L-type amino acid transporters (LATs) are the delivery vehicles that supply them. Metastatic, castration-resistant prostate cancer (CRPC) cells are highly dependent on LATs to deliver the amino acid leucine that the cells need for growth and proliferation.

September 3, 2013

Association between hormone replacement therapy use and breast cancer risk varies by race/ethnicity, body mass index, and breast density Breast cancer risk associated with use of hormone replacement therapy (HRT) among postmenopausal women was variable when analyzed by race/ethnicity, body mass index (BMI), and breast density.

August 28, 2013

Consuming alcohol before first pregnancy linked with increased risk of BBD & breast cancerDrinking alcohol before first pregnancy is associated with an increased risk of benign breast disease (BBD) and breast cancer, independent of drinking after first pregnancy.

August 15, 2013

Consuming a high quality diet is associated with lower risk of pancreatic cancer People who reported dietary intake that was most consistent with the 2005 Dietary Guidelines for Americans had lower risk of pancreatic cancer.

July 26, 2013

HIV-Associated Lymphoma Survival has Not Improved During the Antiretroviral Therapy Era Stable survival rates were observed for HIV-associated lymphoma patients during the antiretroviral therapy (ART) era in the US.

June 17, 2013

Timeline Reforms Increase Initiation Speed of NCI Sponsored Clinical Trials The National Cancer Institute (NCI) and investigators have reduced the deadlines for initiation of trials with the goal of reaching more patients in need of new treatments.

June 16, 2013

Epoetin alfa reduces anemia in breast cancer patients with no negative impact on survival In patients with high-risk breast cancer, addition of the erythropoiesis-stimulating agent (ESA) epoetin alfa to the chemotherapy regimen may help avoid the decrease in hemoglobin levels and resulting anemia often seen in these patients and does not negatively affect relapse-free (RFS) or overall survival (OS). However, it can increase the risk of thrombotic events.

May 30, 2013

TCE Exposure Linked To Increase Risk of Some Cancers Trichloroethylene (TCE) exposure has possible links to increased liver cancer risk, and the relationship between TCE exposure and risks of cancers of low incidence and those with confounding by lifestyle and other factors need further study.

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