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Virus Mentha

NAR Molecular Biology Database Collection entry number 1247
Calderone, Alberto; Licata, Luana; Cesareni, Gianni
Molecular Genetics Group, Department of Biology - Tor Vergata University, Rome, Italy

Database Description

virus mentha archives evidence about viral interactions collected from different sources and presents these data in a complete and comprehensive way. Its data comes from manually curated protein-protein interaction databases that have adhered to the IMEx consortium. virus mentha is a resource that offers a series of tools to analyse selected proteins in the context of a network of interactions. Protein interaction databases archive protein-protein interaction (PPI) information from published articles. However, no database alone has sufficient literature coverage to offer a complete resource to investigate "the interactome".
virus mentha's approach generates every week a consistent interactome (graph). Most importantly, the procedure assigns to each interaction a reliability score that takes into account all the supporting evidence. virus mentha offers direct access to viral families such as: Orthomyxoviridae, Orthoretrovirinae and Herpesviridae plus, it offers the unique possibility of searching by host organism. The website and the graphical application are designed to make the data stored in virus mentha accessible and analysable to all users.

Recent Developments

In December 2014 this resource includes 3984 proteins, 8176 interactions, 8800 publications


1. mentha: a resource for browsing integrated protein-interaction networks (2013) A Calderone, L Castagnoli, G Cesareni Nature Methods 10, 690

Go to the abstract in the NAR 2015 Database Issue.
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