NAR Molecular Biology Database Collection entry number 614
Ogata, H. and Claverie, J.-M.
Information Genomique & Structurale, UPR CNRS 2589, Marseille Cedex 20, France
Metagrowth is a new type knowledge base aiming to guide the experimental studies on the culture conditions of obligate parasitic bacteria. We gathered biological evidences giving clues about the establishment of axenic (i.e. "cell-free") growth of obligate pathogens from various sources including published literature, genomic sequence information, metabolic databases and transporter databases. The database entry is composed of the evidences and specific hypotheses derived from them. Currently 200 entries are available for Rickettsia prowazekii, Rickettsia conorii, Tropheryma whipplei, Treponema pallidum, Mycobacterium tuberculosis and Coxiella burnetii. Its web interface helps the user to efficiently design new axenic culture conditions to test for those bacteria.
We thank Dr. Didier Raoult for helpful discussions.
Category: Genomics Databases (non-vertebrate)
Subcategory: Prokaryotic genome databases
Category: Metabolic and Signaling Pathways
Subcategory: Metabolic pathways
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