Editors
SENIOR EDITORS
Alan Fersht
UK
Valerie Daggett
US
CONSULTING EDITOR
Greg Winter
UK
METHODS EDITOR
Arne Skerra
Germany
EDITORIAL BOARD
Neils Andersen
US
Miniprotein design; beta-sheet models; folding dynamics; NMR; structure analysis
Frances Arnold
US
Directed evolution; cytochrome P450; protein design; in vitro selection; enzyme engineering
P Balaram
India
Protein design; de novo peptide design; protein folding; analysis of motifs; disulfide engineering
Lars Baltzer
Sweden
De novo protein design; (protein design); peptide; bioorganic; catalysis; molecular recognition; reactivity
Hagan Bayley
UK
Biosensors; biomolecular materials [fibers, elastomers, adhesives etc.];chemical modification of proteins; membrane proteins; photochemistry; single molecule biology
Hugues Bedouelle
France
Recombinant antibody; aminoacyl-tRNA; synthetase; biosensor; infectious agent; phage display; protein stability; therapeutic protein
Albert Berghuis
Canada
Structural Biology; structural bioinformatics; computational chemistry; enzyme mechanism; enzyme evolution
Alan Berry
UK
Directed evolution; mechanistic enzymology; aldolases; enzyme engineering
Paula Booth
UK
Carl Borrebaeck
Sweden
Immunotherapy; antibody engineering; target discovery; cancer; lymphomas; B cell developmen; microarrays; proteom analysis; allergy
Stephen Bottomley
Australia
Protein folding and misfolding; protein expression; expression systems; protein aggregation; spectroscopy
Andrew Bradbury
US
Phage display; selection systems; antibodies; fluorescent proteins; GFP; cre/lox recombination
Dennis Burton
US
Antibodies; antibody engineering; virus glycoproteins; HIV; prion proteins
Paul Carter
US
Antibodies; in vitro evolution; therapeutic proteins
Ashutosh Chilkoti
US
Protein based polymers; stimuli responsive polypeptides; protein-polymer conjugates
Jason Chin
UK
Fabrizio Chiti
Italy
Protein misfolding; protein aggregation; protein folding; amyloid fibrils; mechanisms of amyloid formation; protein deposition diseases; amyloid diseases
Brian Clark
Denmark
Protein synthesis; proteomics; protein modification; ageing
Jane Clarke
UK
Protein folding; protein stability; protein dynamics; force spectroscopy; AFM; protein elasticity; single molecule studies
Marius Clore
US
NMR spectroscopy; structural biology; protein-protein interactions; protein-nucleic acid interactions; transcriptionfactors; signal transduction; computational chemistry; structure determination methods; structure prediction
Fred Cohen
US
Protein misfolding; prion diseases; heteropolymer design; protein modeling
Matt Cordes
US
Protein folding; protein evolution ; nuclear magnetic resonance ; conformational switching
Mirek Cygler
Canada
Protein structure; enzymatic mechanism; glycosaminoglycan processing enzymes; proteases and esterases; structural genomics
Alan Davidson
Canada
Protein folding; mutagenesis; SH3 domains; folding and sequence conservation
Michael Deem
US
Statistical mechanics; protein evolution; original antigenic sin
William DeGrado
US
Protein design; bioinorganic chemistry; protein folding
Bauke Dijkstra
Netherlands
Protein structure; enzyme mechanisms; protein engineering; crystallography; biophysical techniques
Christopher Dobson
UK
William Eaton
US
Protein dynamics, folding and self-assembly; sickle cell disease
David Eisenberg
US
Amyloid; domain swapping; prion structure; protein interations; functional networks
Edward Eisenstein
US
Jacques Fastrez
Belgium
Directed evolution; selection for catalytic activity; phage display; proteases; lactamases and peptidases
Angelo Fontana
Italy
Protein folding; proteolysis; biospectroscopy; protein chemistry ; mass spectrometry
Assaf Friedler
Israel
peptides; peptide engineering; protein-protein interactions; biophysics; pharmacological chaperones; medicinal chemistry; HIV-1 proteins; cancer
Stefano Gianni
Italy
Protein folding; structural biology; protein-protein interaction; biophysics; kinetics
Adrian Goldman
Finland
Protein structure; x-ray crystallography; enzyme modification; protein evolution
Richard Goldstein
UK
Protein evolution; protein bioinformatics
Andrew Griffiths
UK
Directed evolution; selection; phage display; antibody selection; enzyme evolution
Angela Gronenborn
US
NMR spectroscopy; protein structure and dynamics; folding and assembly; protein interactions; molecular recognition and signalling
Bernd Gutte
Switzerland
De novo design of functional peptides; protein folding; retro-proteins; phage display of peptide libraries
Michael Hecht
US
Protein design; combinatorial methods; library design; mutagenesis; binary patterning; protein expression
Don Hilvert
Switzerland
Phil Holliger
UK
Directed evolution; repertoire selection; polymerases; replication; nucleotide chemistry
Hennie Hoogenboom
Netherlands
Antibody engineering; protein expression; display methods; molecular evolution; cancer immunotherapy
Nick Hoogenraad
Australia
Molecular chaperones; protein folding; stress response; protein targeting; mitochondrial biogenesis
Amnon Horovitz
Israel
Chaperonins; allostery; mutant cycles; protein folding
Arthur Horwich
US
Molecular chaperones; chaperonins; GroEL; folding in vivo; amyloids; TTR
Peter Hudson
Australia
Protein structure and design; directed molecular evolution; display and selection technologies; protein arrays and biosensors
James Huston
US
Antibody engineering, recombinant fusion proteins and linkers, engineered bispecifics, immunotargeting, antibody therapeutic and imaging agents, intracellular antibody therapy.
Taiji Imoto
Japan
Stabilization; folding; reaction mechanisms; chemical modification; antigenicity
Leo James
UK
Immunology; structural biology/x-ray crystallography; kinetics; biophysics; protein-protein recognition
Dick Janssen
Netherlands
hydrolases; enzyme kinetics; biocatalysis; dehalogenases
Laurent Jespers
UK
Phage display; antibody engineering; molecular evolution; domain antibody
Jeff Kelly
US
Thomas Kiefhaber
Switzerland
Protein folding; protein stability; reaction kinetics; protein dynamics
Andreas Kungl
Austria
Protein engineering; fluorescence; circular dichroism; microcalorimetry; proteomics; molecular dynamics; chemokines
Robin Leatherbarrow
UK
Peptide chemistry; peptide synthesis; protease; protease inhibitor; protein; NMR; enzyme kinetics; enzyme inhibition; molecular interactions
Bengt Mannervik
Sweden
Glutathione; combinatorial protein chemistry; directed evolution; phage display; protein redesign
Susan Marqusee
US
James Marks
US
Andreas Matouschek
US
Protein folding and unfolding; protein degradation; ATP-dependent proteases; protein translocation across membranes; mechanism of protein machines
Brian Matthews
US
Protein crystallography; protein stability; protein design.
Stephen Mayo
US
Protein design; protein stability; combinatorial optimization; molecular modeling; force fields
Liz Meiering
Canada
Protein folding; protein stability; protein misfolding and aggregation
Vadim Mesyanzhinov
Russia
Protein design; foldon; enzybiotics; virus; bacteriophage
Andrew Miranker
US
Protein folding; spectroscopy; amyloid; protein-protein interactions; complex assembly
Kosuke Morikawa
Japan
Protein crystallography; DNA binding protein; ligand receptor interaction
Regina Murphy
US
Protein/Peptide misfolding and aggregation; kinetics of amyloidogenesis; light scattering
Haruki Nakamura
Japan
Structural bioinformatics; protein and proteome databases; structural proteomics; molecular simulation; protein folding
Dario Neri
Switzerland
Therapeutic antibodies; protein libraries and selection methodologies; chelate effect and high-affinity binding; protein-based in vivo targeting, with special emphasis on angiogenesis-related diseases
Feng Ni
Canada
Polypeptide design; signaling protein interactions; binding allostery; instrinsically-unstructured proteins (IUPs); NMR; blood coagulation and antithrombotics
Robin Offord
Switzerland
Chemically synthesized proteins; semisynthetic proteins and peptides; chemokines; HIV receptor antagonists
Mikael Oliveberg
Sweden
David Ollis
Australia
X-ray crystallography; protein structure; function and engineering; directed evolution; enzyme mechanism
Christine Orengo
UK
Protein family classification and analysis, structural genomics
Jane Osbourn
UK
Antibody engineering; phage display; ribosome display; selection technology
Hartmut Oschkinat
Germany
Daniel Otzen
Denmark
Protein folding kinetics; protein stability; membrane protein biophysics; protein fibrillation; surfactants
Evamaria Petersen
Denmark
Protein engineering; molecular directed evolution; lipase; lipid binding proteins
Andreas Plueckthun
Switzerland
Directed evolution; display and selection technologies; ligand binding; protein stability; antibody engineering; protein design
Flemming Poulsen
Denmark
Protein struture; protein folding; protein dynamics protein stability and NMR spectroscopy
Sheena Radford
UK
Folding; misfolding; amyloid; single molecules; AFM
Ron Raines
US
Chemical biology; protein chemistry; enzymology
Daniel Raleigh
US
Amyloid formation and protein aggregation; protein design; protein stability and thermodynamics; NMR
Anthony Rees
Sweden
Antibody modeling; antibody mimetics; artificial receptors
Lynne Regan
US
Protein design; folding; stability; helical proteins; protein-metal interactions; protein-protein interaction; protein-RNA interactions
Heinrich Roder
USA
Protein folding; kinetics; folding intermediates; rapid mixing; NMR; hydrogen exchange
Peter Roepstorff
Denmark
Mass spectrometry; proteomics; post translational modifications; protein interaction
Steven Russell
US
Virotherapy; gene therapy; virus display; targeting; membrane fusion
Andrej Sali
US
Protein structure analysis and modeling; protein assembly analysis and modeling
Mark Sansom
UK
Membrane proteins; ion channels; molecular dynamics; homology modelling
Jeffery G. Saven
US
Harold Scheraga
US
Protein folding; physical chemistry; statistical mechanics; global optimization
Gideon Schreiber
Israel
Protein-protein interaction; binding kinetics; proteomics; protein design; interferon; cooperativity
Klaus Schulten
US
Computational biology; membrane proteins; mechanical proteins; photosynthetic apparatus; nanosystem bioengineering;
Luis Serrano
Germany
Folding; Design; Biocomputing; Amyloid; Structure analysis
P C Shaw
Hong Kong
Molecular biology & protein engineering; protein-protein interaction; ribsome inactivating protein; N-glycosidase; DNA methylase
Arne Skerra
Germany
Rational design; combinatorial selection; antibody engineering; binding proteins; protein crystallography
Dieter Soll
US
Aminoacyl-tRNA synthetases; RNA modification enzymes; RNA; protein interactions
Tobin Sosnick
US
Protein folding; RNA folding; kinetics; hydrogen exchange; small-angle scattering
Patrick Stayton
US
Biohybrid materials; smart protein conjugates; biomineralization
Michael Sternberg
UK
Bioinformatics; protein modelling
Robert Stroud
US
Protein crystallography especially applied to membrane channels and receptors and to drug design aimed at therapeutically important targets
Joel Sussman
Israel
Protein crystallography; bioinformatics; neurobiology; intrinsically unfolded proteins; structural proteomics; halophilic/halotolerant proteins; acetylcholinesterase/butyrylcholinesterase
Lukas Tamm
US
Dan Tawfik
Israel
Enzyme evolution; directed evolution; enzyme mechanisms; protein conformation; antibodies
David Thirumalai
US
Computational and theoretical biophysics; protein folding; protein aggregation; chaperone-mediated folding; single molecule studies
Hans Thøgersen
Denmark
Antibody mimics; protein tinkering; protein-drug design; refolding; large-scale protein processing
Janet Thornton
UK
Computational biology; bioinformatics; structural biology; genomics
Bruce Tidor
US
Computational biology; protein and ligand design; electrostatic interactions; molecular dynamics; protein-DNA interactions; systems biology
Peter Tieleman
Canada
Expertise terms: membrane proteins, protein modeling, biomolecular simulation, membrane biophysics
Jayant Udgaonkar
India
Mathias Uhlen
Sweden
Proteomics; combinatorial selection; affinity purification; expression profiling
Rebecca Wade
Germany
Computational biology; molecular recognition; molecular dynamics; protein and ligand design; molecular simulation
Sally Ward
USA
Rik Wierenga
Finland
Protein crystallography; protein engineering; TIM; CoA; enzymology
Tony Wilkinson
UK
Protein structure; enzyme mechanisms; protein engineering; crystallography; expression systems
Roger Williams
UK
Protein structure; signal transduction; protein/lipid interactions; phosphoinositide signalling
Stephen Withers
Canada
Enzyme mechanisms; glycosyl transfer; glycosidase; carbohydrates
Kambo Wong
Hong Kong
NMR; protein crystallography; protein stability; protein engineering
Dek Woolfson
UK
Structural studies of peptides and proteins; rational protein design; combinatorial design and selection; nanobiotechnology
Anna Wu
US
Recombinant antibody fragments; antibody fusion proteins; molecular imaging; pharmacokinetics; bioconjugation of nanomaterials
Todd Yeates
US
Protein structure and design; x-ray crystallography; symmetry and self-assembly; protein topology and knots, algorithms
Mark Zoller
US
Molecular biology and protein engineering; phage display; protein kinases; GPCRs and ion channels involved in taste and smell
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