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Supplementary Data Guidelines

Supplementary Data is supporting material that cannot be included in the printed version for reasons of space, and that is not essential for inclusion in the full text of the manuscript but would nevertheless benefit the reader. It should not be essential to understanding the conclusions of the paper but should contain data that is additional or complementary and directly relevant to the article content.

Supplementary data will be made available by the publisher as online-only content linked to the online manuscript. Such information includes more detailed methods, extended data sets/data analysis, tables, or additional figures. In addition, other material, including video clips and sound files, that enhance or extend the context of the paper beyond that which can appear in print are welcome.

Supplementary data will be subject to the same editorial standards and peer review process as the printed article and must be submitted along with the main manuscript. The information should be submitted in separate files and clearly designated as "Supplementary." Also ensure that the supplementary data is referred to in the main manuscript at an appropriate point in the text.

We also ask that you provide a brief description of the supplementary data. The information you provide will be used to describe supplementary data content and will appear in the print version after the main body of the article.

When a revised manuscript (after peer review) is submitted, the supplementary data must be submitted once again with final manuscript files. It must be supplied to the production department with the article for publication, not at a later date. It cannot be altered or replaced after the paper has been accepted for publication. Supplementary data will not be copyedited so it is important that the data are clearly and succinctly presented, and that the style of terms conforms with the rest of the paper.

Acceptable formats for Supplementary Data
Files for supplementary data should be clearly marked as such and be accompanied by a summary of the file names and types. A maximum of 5 files is acceptable to make up the supplementary data unit for an article. The maximum size per file should not exceed 2 MB (although text files should be a great deal smaller), and files should be as small as possible, so that they can be downloaded quickly. An HTML index page is created to link the supplementary data file(s) to the article. Please provide short (2-4 word) titles for each individual file-these will be used to create links to the files from the index page.

Recommendations for Supplementary Data


  1. Use a common cross-platform (PC, Mac, Linux/UNIX, etc.) format for supplementary data to allow the greatest access for your readers.

  2. Provide text files in Portable Document Format (.pdf), Microsoft Word (.doc), HTML (.html), or Rich Text Format (.rtf). Files supplied in Word or RTF may be used to create a PDF file.

  3. Provide spreadsheet files in Microsoft Excel (.xls) or CSV (.csv) format.

  4. Provide image files as Tagged Image Format (.tif), Graphic Image Format (.gif), or JPEG (.jpg). Images should be a maximum size of 640 x 480 pixels (9 x 6.8 inches at 72 pixels per inch).

  5. The most commonly accessible format for audio clips is .mp3. Although not recommended, QuickTime, RealMedia, and Windows Media file formats are also acceptable.

  6. The preferred and most common format for movie clips is MPEG Movie (.mpg), although QuickTime Video (.mov) and Microsoft AVI Video (.avi) formats are also acceptable.

If you require further help or information regarding submission or preparation of supplementary data, please contact the Managing Editor at toxsci@toxicology.org or the Production Editor at toxsci@oxfordjournals.org.